Cat Scratch Disease

  • André Luiz Land Curi
Living reference work entry


Cat scratch disease is caused by a gram-negative bacillus called Bartonella henselae.

It was originally described as a cause of Parinaud’s oculoglandular syndrome in the late 1880s. However, intraocular involvement was described in 1970.

Systemic symptoms include fever, lymphadenopathy, headache, and cutaneous rush and occur in approximately 70% of patients.

Intraocular involvement is variable. Correct treatment is still debatable. Prognosis is usually good.


Infectious Mononucleosis Ocular Symptom Positive Serology Ocular Finding Febrile Disease 
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Suggested Reading

  1. Cunningham ET, Koehler JE. Ocular bartonelosis. Am J Ophthalmol. 2000;130:340–9.CrossRefPubMedGoogle Scholar
  2. Curi ALL, Machado DO, Heringer G, et al. Ocular manifestation of cat-scratch disease in HIV+ patients. Am J Ophthalmol. 2006;141(2):400–1.CrossRefPubMedGoogle Scholar
  3. Rolain JM, Brouqui P, Koehler JE, et al. Recommendations for treatment of human infections caused by Bartonella species. Antimicrob Agents Chemother. 2004 Jun;48(6):1921–33.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Solley WA, Martin DF, Newman NJ, et al. Cat-scratch disease-posterior segment manifestations. Ophthalmology. 1999;106:1546–53.CrossRefPubMedGoogle Scholar

Copyright information

© Springer (India) Pvt. Ltd. 2016

Authors and Affiliations

  1. 1.National Institute of Infectious Diseases – INIOswaldo Cruz Foundation – FIOCRUZRio de JaneiroBrazil

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