Fungal endophthalmitis is defined as the intraocular presence of fungi, involving the vitreous and/or the aqueous humors, accompanied by an inflammatory reaction. The epidemiology of fungal endophthalmitis is highly influenced by the environment, the climate, and people living conditions. Endogenous invasion of the eye usually begins with the localization of microorganisms carried by the bloodstream at the level of the choroid or, the retina (fungal chorioretinitis). Exogenous fungal endophthalmitis is usually post-surgical/post traumatic, and can be characterized by a delayed onset and a less aggressive behavior as compared to bacterial.
The treatment of fungal endophthalmitis is based on a combination of systemic and intravitreal antimycotic drugs usually associated with pars plana vitrectomy.
The visual outcome is variable ad depends on a correct management of the disease, on the lesions location, the causative agent and the stage at presentation.
KeywordsOptical Coherence Tomography Anterior Chamber Best Correct Visual Acuity Epiretinal Membrane Posterior Chamber
- Wykoff CC, Flynn HW Jr, Miller D, Scott IU, Alfonso EC. Exogenous fungal endophthalmitis: microbiology and clinical outcomes. Ophthalmology. 2008;115(9):1501–7, 1507.e1–2. doi:10.1016/j.ophtha.2008.02.027.Google Scholar