Anterior Segment Manifestations of Lyme Disease

  • Muhammad Hassan
  • Mohammad Ali Sadiq
  • Aniruddha Agarwal
  • Bahram Bodaghi
  • Quan Dong Nguyen
Living reference work entry


Lyme borreliosis is one of the most common spirochetal infections in the developed world. Ocular manifestations of Lyme disease can potentially occur in any stage of the disease, but it is more common during the second stage of the disease (characterized by involvement of the nervous and cardiac tissue). Lyme disease can affect any ocular structure. However, anterior uveal involvement is an uncommon manifestation of Lyme borreliosis. The characteristic features of anterior Lyme-related uveitis include granulomatous uveitis, which is generally bilateral; however, cases with unilateral manifestations have been reported in the literature. In this chapter, clinical features of anterior uveitis secondary to infection with Borrelia species are outlined.


Lyme Disease Anterior Uveitis Lyme Borreliosis Intermediate Uveitis Posterior Synechia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Bodaghi B. Ocular manifestations of Lyme disease. Med Mal Infect. 2007;37(7–8):518–22.CrossRefPubMedGoogle Scholar
  2. Mikkila HO, Seppala IJ, Viljanen MK, Peltomaa MP, Karma A. The expanding clinical spectrum of ocular lyme borreliosis. Ophthalmology. 2000;107(3):581–7.CrossRefPubMedGoogle Scholar
  3. Mora P, Carta A. Ocular manifestations of Lyme borreliosis in Europe. Int J Med Sci. 2009;6(3):124–5.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Winterkorn JM. Lyme disease: neurologic and ophthalmic manifestations. Surv Ophthalmol. 1990;35(3):191–204.CrossRefPubMedGoogle Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Stanley M. Truhlsen Eye InstituteUniversity of Nebraska Medical CenterOmahaUSA
  2. 2.Department of OphthalmologyHôpital Universitaire Pitié-Salpêtrière, University of ParisParisFrance
  3. 3.Advanced Eye CenterPost Graduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

Personalised recommendations