Juvenile Xanthogranuloma

  • Angela Bessette
  • Francesco Pichi
  • Arun Singh
Living reference work entry


Juvenile xanthogranuloma is a non-Langerhans cell histiocytosis affecting young children. Although primarily a cutaneous disorder, it can affect the eye and its ocular manifestations are diverse. Involvement of the iris, choroid, conjunctiva, eyelid, and orbit have been described. Although typically a benign, self-limited disorder of the skin, ocular involvement can lead to vision-threatening complications, including hyphema, secondary glaucoma, and amblyopia. The clinician must be aware of this uncommon masquerade syndrome as prompt diagnosis and treatment are critical to prevent vision loss.


Cutaneous Manifestation Ocular Involvement Secondary Glaucoma Neovascular Glaucoma Intermediate Uveitis 
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Suggested Reading

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Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Cleveland Clinic FoundationClevelandUSA
  2. 2.Department of Ophthalmic OncologyCole Eye Institute, Cleveland Clinic FoundationClevelandUSA
  3. 3.Cleveland Clinic FoundationClevelandUSA

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