Algorithm for Work-Up of Episcleritis and Scleritis

  • Dinesh Visva Gunasekeran
  • Rupesh Agrawal
Living reference work entry


Episcleritis and scleritis are two important differential diagnoses for a patient with red eye. While episcleritis is a self-limiting condition, scleritis is often associated with systemic autoimmune disease and may lead to severe complications and blindness. A systematic approach is imperative in monitoring and management of patients with episcleritis and scleritis. A brief algorithm for management of red eye is outlined in this chapter with accompanying visual aids.


Optical Coherence Tomography Herpes Zoster Angle Closure Glaucoma Ultrasound Biomicroscopy Acute Angle Closure Glaucoma 
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Suggested Reading

  1. Berchicci L, Miserocchi E, Modorati G, et al. Clinical features of patients with episcleritis and scleritis in an Italian tertiary referral center. Eur J Ophthalmol. 2014;24(3):293–8.CrossRefPubMedGoogle Scholar
  2. Heron E, Gutzwiller-Fontaine M, Bourcier T. Scleritis and episcleritis: diagnosis and treatment. Rev Med Interne. 2014;35(9):577–85.CrossRefPubMedGoogle Scholar
  3. Homayounfar G, Nardone N, et al. Incidence of scleritis and episcleritis: results from the Pacific Ocular Inflammation Study. Am J Ophthalmol. 2013;156(4):752–8.CrossRefPubMedGoogle Scholar
  4. Homayounfar G, Borkar DS, Acharya NR, et al. Clinical characteristics of scleritis and episcleritis: results from the pacific ocular inflammation study. Ocul Immunol Inflamm. 2014;22(5):403–4.CrossRefPubMedGoogle Scholar
  5. Honik G, Wong IG, Gritz DC. Incidence and prevalence of episcleritis and scleritis in Northern California. Cornea. 2013;32(12):1562–6.CrossRefPubMedGoogle Scholar
  6. Nguyen P, Yiu SC. Imaging studies in a case of infectious scleritis after pterygium excision. Middle East Afr J Ophthalmol. 2012;19(3):337–9.CrossRefPubMedPubMedCentralGoogle Scholar
  7. Okhravi N, Odufuwa B, McCluskey P, et al. Scleritis. Surv Ophthalmol. 2005;50:351–63.CrossRefPubMedGoogle Scholar
  8. Ramenaden ER, Raiji VR. Clinical characteristics and visual outcomes in infectious scleritis: a review. Clin Ophthalmol. 2013;7:2113–22.PubMedPubMedCentralGoogle Scholar
  9. Sainz-de-la-Maza M, Jabbur NS, Foster CS. Severity of scleritis and episcleritis. Ophthalmology. 1994;101:389–96.CrossRefPubMedGoogle Scholar
  10. Sainz de la Maza M, Molina N, Foster CS, et al. Clinical characteristics of a large cohort of patients with scleritis and episcleritis. Ophthalmology. 2012;119(1):43–50.CrossRefPubMedGoogle Scholar
  11. Watson PG, Hayreh SS. Scleritis and episcleritis. Br J Ophthalmol. 1976;60(3):163–91.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Clinical Research, Ophthalmology, Tan Tock Seng Hospital (TTSH)SingaporeSingapore
  2. 2.National Healthcare Group Eye Institute, Department of OphthalmologyTan Tock Seng HospitalSingaporeSingapore

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