Melanoma-Associated Retinopathy (MAR)

Living reference work entry


Melanoma associated retinopathy is a rare paraneoplastic syndrome that occurs in patients with cutaneous or systemic melanoma. This condition usually presents with a quiet posterior segment, vascular attenuation, and visual field changes. Immunological changes in this condition lead to characteristic absence of B waves on electroretinography. Diagnosis of melanoma associated retinopathy is relevant because re-staging of the disease and change in the management may be required. In the index chapter, a case of melanoma associated retinopathy has been illustrated.


Cutaneous Melanoma Gamma Globulin Night Blindness Systemic Immunosuppression BRAF Wild Type 
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Suggested Reading

  1. Bahig H, Wein F, Del Maestro RF. Melanoma-associated retinopathy report of a case and review. Can J Neurol Sci. 2011;38:797–8.CrossRefPubMedGoogle Scholar
  2. Rahimy E, Sarraf D. Paraneoplastic and non-paraneoplastic retinopathy and optic neuropathy: evaluation and management. Surv Ophthalmol. 2013;58(5):430–58.CrossRefPubMedGoogle Scholar
  3. Audemard A, de Raucourt S, Miocque S, Comoz F, Giraud JM, Dreno B, Bienvenu B, Rogerie MJ, Dompmartin A. Melanoma-associated retinopathy treated with ipilimumab therapy. Dermatology. 2013;227(2):146–9.CrossRefPubMedGoogle Scholar

Copyright information

© Springer India 2016

Authors and Affiliations

  1. 1.Departments of Ophthalmology and Molecular MedicineMayo ClinicRochesterUSA

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