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UDP-Gal: BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5)

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Handbook of Glycosyltransferases and Related Genes

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Abstract

β3-Galactosyltransferase (β3GalT) transfers galactose from UDP-Gal to N-acetylglucosamine (GlcNAc) with a β1,3-linkage. To date, five members of the β3GalT family have been cloned and analyzed (Isshiki et al. 1999). β3GalT1 was cloned first by an expression cloning method (Sasaki et al. 1994). Three additional members, β3GalT2, β3GalT3*, and β3GalT4, which have sequences homologous to β3GalT1, were identified in the EST database and subsequently cloned (Isshiki et al. 1999; Kolbinger et al. 1998; Amado et al. 1998; Hennet et al. 1998). (*B3GALT3 was renamed B3GALNT1, since the enzymatic activity of β3GalNAcT was found in later studies.)

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Authors and Affiliations

  1. Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), Central-2, 1-1-1 Umezono, Tsukuba, Ibaraki, Japan

    Dr. Akira Togayachi & Prof. Hisashi Narimatsu

Authors
  1. Dr. Akira Togayachi
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  2. Prof. Hisashi Narimatsu
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Corresponding author

Correspondence to Akira Togayachi .

Editor information

Editors and Affiliations

  1. RIKEN-Max-Planck Joint Research Center for Systems Chemical Biology, RIKEN, Wako, Saitama, Japan

    Naoyuki Taniguchi

  2. Department of Biochemistry, Kochi University, Medical School, Nankoku, Kochi, Japan

    Koichi Honke

  3. Sanford Burnham Medical Research Institute, La Jolla, California, USA

    Minoru Fukuda

  4. Research Center for Medical Glycoscience (RCMG), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan

    Hisashi Narimatsu

  5. RIKEN-Max-Planck Joint Research Center for Systems Chemical Biology, RIKEN, Wako, Saitama, Japan

    Yoshiki Yamaguchi

  6. Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

    Takashi Angata

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© 2014 Springer Japan

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Togayachi, A., Narimatsu, H. (2014). UDP-Gal: BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 5 (B3GALT5). In: Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T. (eds) Handbook of Glycosyltransferases and Related Genes. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54240-7_88

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