Abstract
CHST5 and CHST6 are highly homologous genes to each other, not only at exons but also at the entire genes including putative gene regulatory regions and noncoding intron areas, and are localized side by side in chromosome 16q22 in the same direction (Akama et al. 2000). CHST5 and CHST6 are both present in human and other primate genome, but only either of them is found in other mammalian genome, such as mouse, cow, and dog. CHST5 expressed strongly in colon and small intestine (Lee et al. 1999). CHST6 is expressed in cornea and is involved in sulfation of keratan sulfate glycosaminoglycan (Akama et al. 2000).
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Akama, T.O., Fukuda, M.N. (2014). Carbohydrate (N-Acetylglucosamine 6-O) Sulfotransferase 5 and 6 (CHST5,6). In: Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T. (eds) Handbook of Glycosyltransferases and Related Genes. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54240-7_49
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DOI: https://doi.org/10.1007/978-4-431-54240-7_49
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