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Carbohydrate (Chondroitin 4) Sulfotransferase 11-13 (CHST11-13)

  • Osami Habuchi
Reference work entry

Abstract

Chondroitin 4-sulfate, which contains a sulfate group on position 4 of GalNAc residues, is a major component of cartilage proteoglycans (aggrecan). Chondroitin 4-sulfate is also implicated in the cellular interaction with Plasmodium falciparum-infected erythrocytes (Rogerson et al. 1995; Fried and Duffy 1996). Chondroitin 4-sulfotransferase (C4ST) catalyzes the transfer of sulfate to position 4 of GalNAc residues of chondroitin and is involved in the biosynthesis of chondroitin 4-sulfate. Three isoforms of C4ST, C4ST-1, C4ST-2, and C4ST-3, have been cloned (Yamauchi et al. 2000; Hiraoka et al. 2000; Kang et al. 2002).

Keywords

Gene Trap GalNAc Residue Costello Syndrome Aggressive Breast Cancer Cell HRAS Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Advanced Medical Research CenterAichi Medical UniversityNagakuteJapan

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