Carbohydrate (Chondroitin 4) Sulfotransferase 11-13 (CHST11-13)

Reference work entry


Chondroitin 4-sulfate, which contains a sulfate group on position 4 of GalNAc residues, is a major component of cartilage proteoglycans (aggrecan). Chondroitin 4-sulfate is also implicated in the cellular interaction with Plasmodium falciparum-infected erythrocytes (Rogerson et al. 1995; Fried and Duffy 1996). Chondroitin 4-sulfotransferase (C4ST) catalyzes the transfer of sulfate to position 4 of GalNAc residues of chondroitin and is involved in the biosynthesis of chondroitin 4-sulfate. Three isoforms of C4ST, C4ST-1, C4ST-2, and C4ST-3, have been cloned (Yamauchi et al. 2000; Hiraoka et al. 2000; Kang et al. 2002).


Gene Trap GalNAc Residue Costello Syndrome Aggressive Breast Cancer Cell HRAS Gene 


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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Advanced Medical Research CenterAichi Medical UniversityNagakuteJapan

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