Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS)

  • Birgit Weinhold
  • Rita Gerardy-Schahn
  • Anja Münster-Kühnel
Reference work entry


The cytidine monophosphate N-acetylneuraminic acid synthetase (CMAS) catalyzes the activation of the nine-carbon amino sugar N-acetylneuraminic acid (NeuAc) and other sialic acid (Sia) derivatives to the sugar nucleotide cytidine monophosphate N-acetylneuraminic acid (CMP-NeuAc or CMP-Sia) (Kean 1991) by the following reaction:
$$ \mathrm{CTP}+\mathrm{NeuAc}\to \mathrm{CMP}-\mathrm{NeuAc}+\mathrm{PPi} $$


Rainbow Trout Sialic Acid Nuclear Import Neisseria Meningitidis Purine Nucleoside Phosphorylase 
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Copyright information

© Springer Japan 2014

Authors and Affiliations

  • Birgit Weinhold
    • 1
  • Rita Gerardy-Schahn
    • 1
  • Anja Münster-Kühnel
    • 1
  1. 1.Institute for Cellular ChemistryHannover Medical SchoolHannoverGermany

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