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UDP-N-Acetylglucosamine Pyrophosphorylase 1 (UAP1)

  • Hisafumi Okabe
  • Toshiyuki Mio
Reference work entry

Abstract

Uridine-diphospho-N-acetylglucosamine (UDP-GlcNAc) is an essential precursor of N- or O-linked glycosylation in important metabolic processes (Hart et al. 1989; Herscovics and Orlean 1993). It is known as a substrate of chitin synthase, the product of which is essential for fungal cell wall (Cabib et al. 1982; Milewski et al. 2006), and it also plays important roles in cell wall peptidoglycan synthesis and the disaccharide moiety of lipid A in bacteria (Raetz 1996).

Keywords

Malachite Green Neurospora Crassa Fungal Cell Wall cDNA Expression Library Antisperm Antibody 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Chugai Pharmaceutical Co. LTDKamakura, KanagawaJapan
  2. 2.Research DivisionChugai Pharmaceutical Co. LTDKamakura, KanagawaJapan

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