Mannosyl (Alpha-1,3[6?]-)-Glycoprotein Beta-1,4-N-Acetylglucosaminyltransferase, Isozyme C (Putative) (MGAT4C)

  • Tomohiko Taguchi
Reference work entry


The biological roles of asparagine-linked oligosaccharides (N-glycans) on glycoproteins are thought to take place through the interaction of terminal glycan structures and their receptors. The diversity and avidity of the terminal structures, however, are regulated by the core structure of N-glycans (Schachter 1991). In vertebrates from fish to avian, a pentaantennary N-glycan with a bisecting GlcNAc residue is the most highly branched core structure (Fig. 23.1). Pentaantennary N-glycans were found in hen ovomucoid (Parente et al. 1982; Yamashita et al. 1982) and fish egg glycoproteins (Taguchi et al. 1994, 1995).


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Copyright information

© Springer Japan 2014

Authors and Affiliations

  1. 1.Laboratory of Pathological Cell Biology, Graduate School of Pharmaceutical SciencesUniversity of TokyoTokyoJapan

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