Handbook of Glycosyltransferases and Related Genes pp 1249-1254 | Cite as
ALG Mannosyltransferases, ER Lumen = Alpha Linkage (ALG3,9,12)
N-linked protein glycosylation initiates in the endoplasmic reticulum by the assembly of the Glc3Man9GlcNAc2 oligosaccharide on the lipid carrier dolichylpyrophosphate. This oligosaccharide is transferred by oligosaccharyltransferase to selected asparagine residues of different polypeptide chains translocated into the lumen of the ER.
KeywordsALG3 Protein ALG3 Activity Mannosyl Residue Mutate Yeast Cell Multiple Transmembrane Domain
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