High Pressures and Eukaryotes
General Effects of High Hydrostatic Pressures in Biological Systems
The effects of high hydrostatic pressure in biological systems have been mainly investigated from the following perspectives: (1) structural perturbation of macromolecules such as proteins and lipids, and kinetic analysis of biochemical reactions; (2) microbial adaptation to high pressure in mesophiles and piezophiles; and (3) inactivation of food-spoiling microbes, and applications in nonthermal food processing. During the past decades, an increasing number of innovative high-pressure studies on biological processes have been performed by applying advanced techniques of genetics and molecular biology in bacteria and yeasts as model organisms (Horikoshi 1998; Abe et al. 1999; Abe and Horikoshi 2001; Bartlett 2002; Abe 2004, 2007a; Aertsen et al. 2009). Recent studies in this field have revealed the potential of a broad range of microbes to adapt and develop resistance to increasing hydrostatic pressure and have shown...
KeywordsHydrostatic Pressure High Hydrostatic Pressure Neutral Trehalase Tryptophan Uptake Tryptophan Availability
- Domitrovic T, Fernandes CM, Boy-Marcotte E, Kurtenbach E (2006) High hydrostatic pressure activates gene expression through Msn2/4 stress transcription factors which are involved in the acquired tolerance by mild pressure precondition in Saccharomyces cerevisiae. FEBS Lett 580:6033–6038PubMedCrossRefGoogle Scholar
- Frey B, Janko C, Ebel N, Meister S, Schlucker E, Meyer-Pittroff R, Fietkau R, Herrmann M, Gaipl US (2008) Cells under pressure - treatment of eukaryotic cells with high hydrostatic pressure, from physiologic aspects to pressure induced cell death. Curr Med Chem 15:2329–2336PubMedCrossRefGoogle Scholar
- Giaever G, Chu AM, Ni L, Connelly C, Riles L, Veronneau S, Dow S, Lucau-Danila A, Anderson K, Andre B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Guldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kotter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418:387–391PubMedCrossRefGoogle Scholar