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„Assisted Hatching“

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Reproduktionsmedizin

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Die Eröffnung der Zona pellucida bei menschlichen Embryonen im Rahmen der assistierten Reproduktion ist eine etablierte Technik und wird insbesondere für Assisted Hatching und die Embryo- und Blastozystenbiopsie eingesetzt. Assisted Hatching soll es dem Embryo ermöglichen, zuverlässig aus der ihn umgebenden Zonahülle schlüpfen und anschließend implantieren zu können. Eine korrekte und zeitlich adaptierte Anwendung des Assisted Hatching ist Voraussetzung für das erfolgreiche Schlüpfen. Assisted Hatching kann mit verschiedenen Techniken durchgeführt werden. Der Einsatz von kontakt-freien Lasersystemen hat sich durchgesetzt, um reproduzierbare Öffnungen zu erzeugen. Aufgrund klinischer Daten kann der Einsatz des AH bei Patientinnen mit wiederholtem Implantationsversagen und unter Berücksichtigung von Transfers mit kryokonservierten Embryonen empfohlen werden. Eine Steigerung der Erfolgsraten ist nur bei einem standardisierten Vorgehen zu erwarten.

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Authors and Affiliations

  1. ilabcomm GmbH, St. Augustin, Deutschland

    Markus Montag

  2. Klinik für Gynäkologische Endokrinologie und Reproduktionsmedizin, Universität Innsbruck, Innsbruck, Österreich

    Bettina Toth

Authors
  1. Markus Montag
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  2. Bettina Toth
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Corresponding author

Correspondence to Markus Montag .

Editor information

Editors and Affiliations

  1. Facharzt-Zentrum für Kinderwunsch, Pränatale Medizin, Endokrinologie und Osteologie Hamburg GmbH, amedes experts, Hamburg, Germany

    Klaus Diedrich

  2. SYNLAB Holding Deutschland GmbH, Augsburg, Hamburg, Germany

    Michael Ludwig

  3. Sektion für gynäkologische Endokrinologie und Reproduktionsmedizin, UNIVERSITÄTSKLINIKUM Schleswig-Holstein – Campus Lübeck, Lübeck, Schleswig-Holstein, Germany

    Georg Griesinger

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© 2018 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature

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Montag, M., Toth, B. (2018). „Assisted Hatching“. In: Diedrich, K., Ludwig, M., Griesinger, G. (eds) Reproduktionsmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-55601-6_27-1

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  • DOI: https://doi.org/10.1007/978-3-662-55601-6_27-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-55601-6

  • Online ISBN: 978-3-662-55601-6

  • eBook Packages: Springer Referenz Medizin

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