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Nichtgerminale Hodentumoren

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Uroonkologie

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

90 % aller Hodentumoren gehen von den Keimzelltumoren aus. Die restlichen 10 % aller testikulären Neoplasien gehen histologisch aus sieben verschiedenen Gewebsabschnitten des Hodens hervor. Am häufigsten sind mit 38 % aller nichtgerminalen Tumoren (4 % aller Hodentumoren) die malignen Lymphome. Dies sind überwiegend B-Zell Lymphome, von denen ein Drittel beidseitig auftritt. Nach Ablatio testis ist eine Anthrazyklin-haltige Chemotherapie erforderlich. Die mittlere 5-Jahresüberlebensrate liegt bei etwa 60 %. Keimstrang/Stromatumoren sind mit 26 % die zweithäufigste Gruppe der nichtgerminalen Tumoren. Hierzu zählen die Leydigzelltumoren, die seltenen Sertolizelltumoren und die extrem seltenen Granulosazelltumoren. Mehr als 90 % dieser Tumoren sind gutartig und können durch organerhaltende Exzision behandelt werden. Aufgrund der Seltenheit dieser Tumoren gibt es keine Leitlinien-basierten Therapieempfehlungen. Bei den seltenen malignen Verlaufsformen dieser Tumoren ist die retroperitoneale Lymphadenektomie indiziert. Alle übrigen Entitäten aus der Gruppe der nichtgerminalen Tumoren gelten als extreme Raritäten.

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  1. Urologische Abteilung, Asklepios Klinik Altona, Hamburg, Deutschland

    Klaus-Peter Dieckmann

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  1. Helios Marien Klinikum Duisburg, Duisburg, Nordrhein-Westfalen, Germany

    Herbert Rübben

  2. Urologische Klinik/Poliklinik, Universitätsklinikum Rostock, Rostock, Mecklenburg-Vorpommern, Germany

    Oliver Hakenberg

  3. Klinik und Poliklinik für Urologie , Universitätsklinikum Jena, Jena, Thüringen, Germany

    Marc-Oliver Grimm

  4. Caritaskrankenhaus St. Josef, Regensburg, Germany

    Maximilian Burger

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Dieckmann, KP. (2019). Nichtgerminale Hodentumoren. In: Rübben, H., Hakenberg, O., Grimm, MO., Burger, M. (eds) Uroonkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54652-9_72-1

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