Encyclopedia of Continuum Mechanics

Living Edition
| Editors: Holm Altenbach, Andreas Öchsner

A Modeling Framework for Computational Physiology

Living reference work entry

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DOI: https://doi.org/10.1007/978-3-662-53605-6_29-2


Physics based – the use of physical principles such as the laws of conservation of mass and conservation of energy.

Computational physiology – the use of computer models containing equations that represent physiological processes and the solution of these equations with numerical methods designed for digital computers (such as the finite element methods discussed in this entry).

Multiscale modeling – the use of mathematical models that incorporate physical processes operating at more than one spatial scale (e.g., at the level of cells as well as a whole organ).

Standards-based computational frameworks – this refers to the use of community-agreed standards for the encoding of models to help ensure that they are reproducible and reusable.


Anatomy and physiology are the disciplines that underpin the practice of medicine. Discoveries from molecular biology, including the sequencing of the human genome in 2000 (https://en.wikipedia.org/wiki/Human_genome), are...

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Authors and Affiliations

  1. 1.Auckland Bioengineering InstituteUniversity of AucklandAucklandNew Zealand

Section editors and affiliations

  • Daniel Balzani
    • 1
  1. 1.Ruhr-Universität BochumBochumGermany