Zusammenfassung
Der Mensch besitzt wie kein anderes Säugetier ekkrine Schweißdrüsen, die über die gesamte Haut verteilt sind und effektiv vor einem Hitzestau schützen. Axillär und genitoanal finden sich apokrine Schweißdrüsen, die ab der Pubertät Duftstoffe mit pheromonartiger Wirkung freisetzen. Krankhaftes Schwitzen (Hyperhidrose) kann als rein funktionelle Störung ohne erkennbare Ursache (primär) oder als Folge anderer Erkrankungen (sekundär) auftreten und erhebliche psychosoziale Probleme verursachen. Fehlendes Schwitzen (Anhidrose) kann dagegen zu lebensbedrohlicher Überhitzung führen. Auch krankhafte Geruchsbildung (Bromhidrose) und Verfärbung des Schweißes (Chromhidrose) sind möglich. Entzündlichen Erkrankungen mit histologisch erkennbaren Veränderungen umfassen Miliaria und neutrophile Hidradenitis. Seltene Gendefekte können neben Haar-, Nagel- oder Zahndefekten auch zur Alteration von Schweißdrüsen führen.
This is a preview of subscription content, log in via an institution.
Literatur
Anatomie und Physiologie
Groscurth P (2002) Anatomy of sweat glands. Curr Probl Dermatol 30:1–9
Saga K (2002) Structure and function of human sweat glands studied with histochemistry and cytochemistry. Prog Histochem Cytochem 37:323–386
Sato K, Kang WH, Saga K et al (1989) Biology of sweat glands and their disorders. I. Normal sweat gland function. J Am Acad Dermatol 20:537–563
Hyperhidrose und Hypohidrose
Bahar R, Zhou P, Liu Y et al (2016) The prevalence of anxiety and depression in patients with or without hyperhidrosis (HH). J Am Acad Dermatol 75:1126–1133
Bundesamt für Risikobewertung (2014) Aluminiumhaltige Antitranspirantien tragen zur Aufnahme von Aluminium bei. Stellungnahme Nr. 007/2014. www.bfr.bund.de
Cruddas L, Baker DM (2017) Treatment of primary hyperhidrosis with oral anticholinergic medications: a systematic review. J Eur Acad Dermatol Venereol. https://doi.org/10.1111/jdr.14081
Doolittle J, Walker P, Mills T et al (2016) Hyperhidrosis: an update on prevalence and severity in the United States. Arch Dermatol Res 308:743–749
Du Q, Lin M, Yang JH et al (2016) Overexpression of AQP5 was detected in axillary sweat glands of primary focal hyperhidrosis patients. Dermatology 232:150–155
Heckmann M, Ceballos-Baumann AO, Plewig G (2001) Botulinum toxin A for axillary hyperhidrosis (excessive sweating). N Engl J Med 344:488–493
Hoorens I, Ongenae K (2012) Primary focal hyperhidrosis: current treatment options and a step-by-step approach. JEADV 26(1): 18
Schick CH, Grallath T, Schick KS et al (2016) Radiofrequency thermotherapy for treating axillary hyperhidrosis. Dermatol Surg 42:624–630
Shayesteh A, Boman J, Janlert U et al (2016) Primary hyperhidrosis: implications on symptoms, daily life, health and alcohol consumption when treated with botulinum toxin. J Dermatol 43:928–933
Tu Y, Luo R, Li X et al (2012) Hypermyelination and overexpression of neuregulin-1 in thoracic sympathetic nerves in patients with primary palmar hyperhidrosis. J Clin Neurosci 19:1651–1653
Walling HW (2011) Clinical differentiation of primary from secondary hyperhidrosis. J Am Acad Dermatol 64:690–695
Worle B, Rapprich S, Heckmann M (2012) Definition und Behandlung der primären Hyperhidrose. AWMF-online: http://www.awmf.org
Bromhidrose und Chromhidrose
Guillet G, Zampetti A, Aballain CM (2000) Correlation between bacterial population and axillary and plantar bromidrosis: study of 30 patients. Eur J Dermatol 10:41–42
Heckmann M, Kutt S, Dittmar S et al (2007) Making scents: improvement of olfactory profile after botulinum toxin-A treatment in healthy individuals. Dermatol Surg 33:81–87
Messenger J, Clark S, Massick S et al (2013) A review of trimethylaminuria: (fish odor syndrome. J Clin Aesthet Dermatol 6:45–48
Semkova K, Gergovska M, Kazandjieva J et al (2015) Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. Clin Dermatol 33:483–491
Entzündliche Erkrankungen der Schweißdrüsen
Beham A, Strom K, Weigl LB et al (2002) Die rekurrierende palmoplantare Hidradenitis im Kindesalter. Hautarzt 53:34–36
Copaescu AM, Castilloux JF, Chababi-Atallah M et al (2013) A classic clinical case: neutrophilic eccrine hidradenitis. Case Rep Dermatol 5:340–346
Fujita K, Hatta K (2013) Acquired generalized anhidrosis: review of the literature and report of a case with lymphocytic hidradenitis and sialadenitis successfully treated with cyclosporine. Dermatology 227:270–277
Haque MS, Hailu T, Pritchett E et al (2013) The oldest new finding in atopic dermatitis: subclinical miliaria as an origin. JAMA Dermatol 149:436–438
Story SG, Beschloss JK, Dolan CK et al (2012) Eccrine squamous syringometaplasia associated with vemurafenib therapy. J Am Acad Dermatol 67:e208–e210
Tey HL, Tay EY, Cao T (2015) In vivo imaging of miliaria profunda using high-definition optical coherence tomography: diagnosis, pathogenesis, and treatment. JAMA Dermatol 151:346–348
Wenzel FG, Horn TD (1998) Non-neoplastic disorders of the eccrine glands. J Am Acad Dermatol 38:1–17
Erstbeschreiber
Fox GH, Fordyce JA (1902) Two cases of a rare papular disease affecting the axillary region. J Cutan Genit Dis 20:1–5
Frey L (1923) Le syndrome du nerf auriculo-temporal. Rev Neurol (Paris) 2:97–104
Harrist TJ, Fine JD, Berman RS et al (1982) Neutrophilic eccrine hidradenitis. A distinctive type of neutrophilic dermatosis associated with myelogenous leukemia and chemotherapy. Arch Dermatol 118:263–266
Helweg-Larsen HF, Ludvigsen K (1946) Congenital familial anhidrosis and neurolabyrinthitis. Acta Derm Venereol 26:489–505
Humbert JR, Hammond KB, Hathaway WE et al (1970) Trimethylaminuria: the fish-odour syndrome. Lancet 2:770–771
Hurt MA, Halvorson RD, Petr FC Jr et al (1990) Eccrine squamous syringometaplasia. A cutaneous sweat gland reaction in the histologic spectrum of ‚chemotherapy-associated eccrine hidradenitis‘ and ‚neutrophilic eccrine hidradenitis‘. Arch Dermatol 126:73–77
Jadassohn J (1901) Ueber eine eigenartige Erkrankung der Nasenhaut bei Kindern („Granulosis rubra nasi“). Arch Dermatol Syph (German) 58:145–158
Kasraee B, Masouye I, Piguet V (2009) Playstation palmar Hidradenitis. Br J Dermatol 160:881–898
Lance JW, Drummond PD, Gandevia SC et al (1988) Harlequin syndrome: the sudden onset of unilateral flushing and sweating. J Neurol Neurosurg Psychiatry 51:635–642
Robinson AF (1884) Miliaria and sudamina. J Cutan Venereol Dis 2:362–365
Ross AT (1958) Selective sudomotor denervations. Neurology 8:809–817
Shelley WB, Levy EJ (1956) Apocrine sweat retention in man. II. Fox-Fordyce disease (apocrine miliaria). AMA Arch Derm 73:38–49
Stahr BJ, Cooper PH, Caputo RV (1994) Idiopathic plantar hidradenitis: a neutrophilic eccrine hidradenitis occurring primary in children. J Cutan Pathol 21:289–296
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2018 © Springer-Verlag GmbH Deutschland
About this entry
Cite this entry
Heckmann, M. (2018). Erkrankungen der Schweißdrüsen. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco's Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49546-9_72-1
Download citation
DOI: https://doi.org/10.1007/978-3-662-49546-9_72-1
Received:
Accepted:
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-49546-9
Online ISBN: 978-3-662-49546-9
eBook Packages: Springer Referenz Medizin