Schweißdrüsentumoren mit apokriner und ekkriner Differenzierung

Living reference work entry
Part of the Springer Reference Medizin book series (SRM)

Zusammenfassung

Einige der bekannten Schweißdrüsenkarzinome können sich aus benignen vorbestehenden Schweißdrüsentumoren entwickeln. Daher ist die Kenntnis des morphologischen Spektrums dieser Tumoren erforderlich, um den Übergang in ein Karzinom diagnostizieren zu können. Wichtige Malignitätskriterien sind zunehmende zytologische Atypien, Mitosen,Nekrosen, ein infiltrierendes Tumorwachstum mit perineuralen Tumorausläufern und intralymphatische Tumorzellen. Besondere Vorsicht ist insbesondere bei der Diagnostik des mikrozystischen Adnexkarzinoms angebracht. Da zytologische Malignitätskriterien fehlen und kaum Mitosen nachweisbar sind, ist es histologisch erforderlich, das infiltrierende Wachtumsmuster als wichtigstes und manchmal alleiniges Malignitätskriterium darzustellen. Die Diagnostik gelingt nur bei ausreichend tiefen Biopsien. Oberflächliche Biopsien, die es nicht gestatten, das Wachstumsmuster zu beurteilen, sollten nicht dazu verleiten, voreilig einen gutartigen Schweißdrüsentumor zu diagnostizieren.

Das digitale papilläre Adenokarzinom stellt ein breites Tumorspektrum dar mit vermeintlich gutartigen Läsionen auf der einen Seite und klaren Karzinomen auf der anderen Seite. Nur die genaue Kenntnis dieses Spektrums gestattet es, mit ausreichender diagnostischer Sicherheit die gutartig wirkenden Tumoren als Karzinome zu diagnostizieren.

Weiterführende Literatur

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Weiterführende Literatur zum Porom

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Weiterführende Literatur zum Spiradenom

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Weiterführende Literatur zu Syringofibroadenom

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Weiterführende Literatur zu gutartigen Schweißdrüsentumoren

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Weiterführende Literatur zum Porokarzinom

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Weiterführende Literatur zum Spiradenokarzinom

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Weiterführende Literatur zum Zylindrokarzinom

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Weiterführende Literatur zum malignen Mischtumor

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Weiterführende Literatur zum adenoid-zystischen Karzinom

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Weiterführende Literatur zum mikrozystischen Karzinom

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Weiterführende Literatur zum muzinösen Karzinom

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Weiterführende Literatur zum apokrinen kribiformen Adenokarzinom

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Weiterführende Literatur zum digitalen papillären Adenokarzinom

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Weiterführende Literatur zum Hidradenokarzinom

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Weiterführende Literatur zum extramammären Morbus Paget

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Weiterführende Literatur zu seltenen Schweißdrüsenkarzinomen

  1. Chamberlain RS, Huber K et al (1999) Apocrine gland carcinoma of the axilla: review of the literature and recommendations for treatment. Am J Clin Oncol 22:131PubMedGoogle Scholar
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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Dermatologische GemeinschaftspraxisFriedrichshafenDeutschland

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