Infection with both Trypanosomabrucei gambiense and T. b. rhodesiense lead to diseases called sleeping sickness and/or trypanosomiasis. Although the agents of this disease are subspecies of the same Trypanosoma brucei species, they differ in many general aspects (Table 1) and in their introduced clinical symptoms which can be grouped into two successive phases:
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Further Readings
Barrel MP et al (2007) Human African trypanosomiasis. Br J Pharmacol 152:1155–1171
Brun R et al (2010) Human African trypanosomiasis. Lancet 375:148–159
Priotto G et al (2009) Nifurtimox-eflornithine combination therapy for second stage African T. b. gambiense trypanosomiasis. Lancet 374:56–64
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Mehlhorn, H. (2016). Sleeping Sickness: Humans – Symptoms. In: Mehlhorn, H. (eds) Encyclopedia of Parasitology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43978-4_4332
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