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Immunoglobulin A Nephropathies in Children (Includes HSP)

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Abstract

Immunoglobulin A (IgA) nephropathy (IgAN) was first described in 1968 by Berger and Hinglais [1] and is now recognized as a distinct clinicopathologic entity with a higher frequency worldwide than any other primary glomerulopathy [2]. It was initially considered a benign condition, but extended follow-up of patients indicated that 20–50 % of adults would ultimately progress to end-stage renal failure [2, 3]. Likewise, the favorable prognosis initially attributed to children with IgAN must be questioned in the light of studies [4–8].

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Nakanishi, K., Yoshikawa, N. (2016). Immunoglobulin A Nephropathies in Children (Includes HSP). In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N., Emma, F., Goldstein, S. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43596-0_28

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