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SpringerReference Innere Medizin pp 1–11Cite as

Brugada-Syndrom

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Zusammenfassung

Das Brugada-Syndrom ist eine erbliche, heterogene Ionenkanalerkrankung (MIM-Eintrag: 601144), die durch charakteristische rechtspräkordiale EKG-Veränderungen, dem Fehlen von strukturellen Herzauffälligkeiten und einem erhöhten Risiko für den plötzlichen Herztod gekennzeichnet ist. Typische Symptome sind Synkopen, Kammerflimmern bzw. überlebter plötzlicher Herztod, nächtliche agonale Respiration, Palpitationen und/oder Missempfindungsstörungen im Brustkorbbereich. Diese Symptome entstehen überwiegend in Ruhe bzw. Schlaf, während eines Fieberanstiegs oder unter vagotonen Bedingungen. Das Syndrom wird durch eine Typ-1-ST-Segment-Elevation (Typ-1-EKG) diagnostiziert. Eine spezifische dauerhafte Medikation zur Behandlung des Brugada-Syndroms ist nicht verfügbar. Eine ICD-Behandlung ist derzeit die einzige effektive Strategie zur Verhinderung des plötzlichen Herztodes bei Patienten mit Brugada-Syndrom.

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Authors and Affiliations

  1. Institut für Genetik von Herzerkrankungen (IfGH), Department für Kardiologie und Angiologie, Universitätsklinikum Münster (UKM), Albert-Schweitzer-Campus 1 (Gebäude D3), 48149, Münster, Deutschland

    Eric Schulze-Bahr

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  1. Eric Schulze-Bahr
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Correspondence to Eric Schulze-Bahr .

Editor information

Editors and Affiliations

  1. Medizinische Klinik I, Universitätsklinikum Schleswig-Hoslstein, Campus Lübeck, Lübeck, Schleswig-Holstein, Germany

    Hendrik Lehnert

  2. TU Dresden Universitätsklinikum Carl Gustav Carus, Dresden, Germany

    Sebastian M. Schellong

  3. FB Gastroenterologie und Hepatologie, Universitätsklinikum Leipzig Medizinische Klinik und Poliklinik II, Leipzig, Sachsen, Germany

    Joachim Mössner

  4. Krankenhaus Barmherzige Brüder, Regensburg, Germany

    Cornel C. Sieber

  5. Nürnberg, Bayern, Germany

    Walter Swoboda

  6. Universitätsklinikum Giessen und Marburg Klinik für Innere Medizin, Marburg, Hessen, Germany

    Andreas Neubauer

  7. Interdisziplinärer Schwerpunkt für Hämos, Universitätsklinikum Gießen und Marburg, Gießen, Germany

    Bettina Kemkes-Matthes

  8. Klinik für Gastroenterologie,Hepatologie, Medizinische Hochschule Hannover, Hannover, Germany

    Michael P. Manns

  9. Sektion für Molekulare und Klinische Inf, Universitätsklinikum Schleswig-Holstein,, Lübeck, Germany

    Jan Rupp

  10. Abt. Kardiologie und Pneumologie, Universitätsklinikum Göttingen Herzzentrum Göttingen, Göttingen, Germany

    Gerd Hasenfuß

  11. Abt. Nephrologie und Klinische Immunologie, Univ.Klinikum Aachen Medizinische Klinik II, Aachen, Germany

    J. Floege

  12. Universitätsklinikum Köln Klinik I für Innere Medizin, Köln, Germany

    Michael Hallek

  13. Klinik für Pneumologie, Medizinische Hochschule Hannover (MHH) Zentrum Innere Medizin, Hannover, Germany

    Tobias Welte

  14. Klinik u. Poliklinik für Innere Medizin, Universitätsmedizin Greifswald, Greifswald, Germany

    Markus Lerch

  15. Dr.-Horst-Schmidt-Kliniken GmbH, Wiesbaden, Germany

    Elisabeth Märker-Hermann

  16. Klinische Toxikologie, Giftinformation, Universitätsklinikum Mainz II. Medizinische Klinik und Poliklinik, Mainz, Germany

    Ludwig Sacha Weilemann

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Schulze-Bahr, E. (2015). Brugada-Syndrom. In: Lehnert, H., et al. SpringerReference Innere Medizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54676-1_199-1

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  • DOI: https://doi.org/10.1007/978-3-642-54676-1_199-1

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