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Erworbene Koagulopathien bei Kindern und Jugendlichen

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Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Die erworbene Koagulopathie ist eine Störung der sekundären Hämostase durch Synthesedefizite, immunologische oder medikamentöse Faktoren.

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Literatur

  • Andrew M, Vegh P, Johnston M, Bowker J, Ofosu F, Mitchell L (1992) Maturation of the hemostatic system during childhood. Blood 80:1998–2005

    CAS  PubMed  Google Scholar 

  • Aschka I, Aumann V, Bergmann F et al (1996) Prevalence of factor V Leiden in children with thrombo-embolism. Eur J Pediatr 155:1009–1014

    Article  CAS  PubMed  Google Scholar 

  • Aster RH (1995) Heparin-induced thrombocytopenia and thrombosis. N Engl J Med 332:1374–1376

    Article  CAS  PubMed  Google Scholar 

  • Bazzano LA, Reynolds K, Holder KN, He J (2006) Effect of folic acid supplementation on risk of cardiovascular diseases: A meta-analysis of randomized controlledtrials. JAMA 296:2720–2726

    Article  CAS  PubMed  Google Scholar 

  • Bertina RM (1998) The prothrombin 20210 G to A variation and thrombosis. Curr Opin Hematol 5:339–342

    Article  CAS  PubMed  Google Scholar 

  • Bertina RM, Koeleman BP, Koster T et al (1994) Mutation in blood coagulation factor V associated with resistance to activated Protein C [see comments]. Nature 369:64–67

    Article  CAS  PubMed  Google Scholar 

  • Bick RL (1998) Disseminated intravascular coagulation: pathophysiological mechanisms and manifestations. Semin Thromb Hemost 24:3–18

    Article  CAS  PubMed  Google Scholar 

  • Brenner B, Sanchez-Vega B, Wu SM, Lanir N, Stafford DW, Solera J (1998) A missense mutation in gamma-glutamyl carboxylase gene causes combined deficiency of all vitamin K-dependent blood coagulation factors. Blood 92:4554–4559

    CAS  PubMed  Google Scholar 

  • Broze GJ Jr (1995) Tissue factor pathway inhibitor. Thromb Haemost 74:90–93

    CAS  PubMed  Google Scholar 

  • Cooper DN, Millar DS, Wacey A, Banner DW, Tuddenham EG (1997a) Inherited factor VII deficiency: molecular genetics and pathophysiology. Thromb Haemost 78:151–160

    CAS  PubMed  Google Scholar 

  • Cooper DN, Millar DS, Wacey A, Pemberton S, Tuddenham EG (1997b) Inherited factor X deficiency: molecular genetics and pathophysiology. Thromb Haemost 78:161–172

    CAS  PubMed  Google Scholar 

  • Dahlback B, Carlsson M, Svensson PJ (1993) Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated Protein C: Prediction of a cofactor to activated Protein C [see comments]. Proc Natl Acad Sci U S A 90:1004–1008

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • David M, Andrew M (1993) Venous thromboembolic complications in children. J Pediatr 123:337–346

    Article  CAS  PubMed  Google Scholar 

  • David M, Manco-Johnson M, Andrew M (1995) Diagnosis and treatment of venous thromboembolism in children and adolescents. On behalf of the subcommittee on perinatal haemostasis of the scientific and standardization committee of the ISTH. Thromb Haemost 74:791–792

    CAS  PubMed  Google Scholar 

  • Eichinger S, Pabinger I, Stümpflen A et al (1997) The risk of recurrent venousthromboembolism in patients with and without factor V Leiden. Thromb Haemost 77:624–628

    CAS  PubMed  Google Scholar 

  • Engesser L, Broekmans AW, Briet E, Brommer EJP, Bertina RM (1987) Hereditary protein S deficiency: clinical manifestations. Ann Intern Med 106:677–682

    Article  CAS  PubMed  Google Scholar 

  • Fisher S, Rikover M, Naor S (1966) Factor 13 deficiency with severe hemorrhagic diathesis. Blood 28:34–39

    CAS  PubMed  Google Scholar 

  • Furie B, Furie BC (1990) Molecular basis of vitamin K-dependent gamma-carboxylation. Blood 75:1753–1762

    CAS  PubMed  Google Scholar 

  • George JN, Woolf SH, Raskob GE et al (1996) Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology [see comments]. Blood 88:3–40

    CAS  PubMed  Google Scholar 

  • Griffin JH, Evatt B, Zimmerman TS, Kleiss AJ, Wideman C (1981) Deficiency of protein C in congenital thrombotic disease. J Clin Invest 68:1370–1373

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Higham JM, O'Brien PM, Shaw RW (1990) Assessment of menstrual blood loss using a pictorial chart. Br J Obstet Gynaecol 97:734–739

    Article  CAS  PubMed  Google Scholar 

  • Ingram GIC (1997) The history of haemophilia. Haemophilia 3(Suppl 1):5–15

    Article  Google Scholar 

  • Kuhle S, Lane DA, Jochmanns K, Male C, Quehenberger P, Lechner K, Pabinger I (2001) Homozygous antithrombin deficiency type II (99 Leu to Phe mutation) and childhood thromboembolism. Thromb Haemost 86:1007–1011

    CAS  PubMed  Google Scholar 

  • Lillicrap D (1998) The molecular basis of haemophilia B. Haemophilia 4:350–357

    Article  CAS  PubMed  Google Scholar 

  • Mammen EF (1983) Factor V deficiency. Semin Thromb Hemost 9:1–72

    Article  CAS  PubMed  Google Scholar 

  • Mannucci PM (1998a) Hemostatic drugs. N Engl J Med 339:245–253

    Article  CAS  PubMed  Google Scholar 

  • Mannucci PM (1998b) Haemophilia treatment protocols around the world: towards a consensus. Haemophilia 4:421

    Article  CAS  PubMed  Google Scholar 

  • Mannucci PM (1998c) Treatment of von Willebrand disease. Haemophilia 4:661–664

    Article  CAS  PubMed  Google Scholar 

  • McDonagh J, Carrell N, Lee MH (1994) Dysfibrinogenemia and other disorders of fibrinogen structure and function. In: Colman RW, Hirsh J, Marder VJ, Salzman JB (Hrsg) Hemostasis and thrombosis: basic principles and clinical practice, 3. Aufl. Lippincott, Philadelphia, S 314–334

    Google Scholar 

  • Peake I (1998) The molecular basis of haemophilia A. Haemophilia 4:346–349

    Article  CAS  PubMed  Google Scholar 

  • Ragni MV, Sinha D, Seaman F, Lewis JH, Spero JA, Walsh PN (1985) Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds. Blood 65:719–724

    CAS  PubMed  Google Scholar 

  • Remond-O’Donnell E, Rosen FS, Kenney DM (1996) Defects in Wiskott-Aldrich syndrome blood cells. Blood 87:2621–2631

    Google Scholar 

  • Rost S, Fregin A, Ivaskevicius V et al (2004) Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 427:537–541

    Article  CAS  PubMed  Google Scholar 

  • Ruggeri ZM (1991) Structure and function of von Willebrand factor: relationship to von Willebrand’s disease. Mayo Clin Proc 66:847–861

    Article  CAS  PubMed  Google Scholar 

  • Schneppenheim R, Budde U (2011) von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein. J Thromb Haemost 9(Suppl 1):209–215

    Article  CAS  PubMed  Google Scholar 

  • Schneppenheim R, Thomas KB, Sutor AH (1995) Von Willebrand disease in childhood. Semin Thromb Hemost 21:261–275

    Article  CAS  PubMed  Google Scholar 

  • Schneppenheim R, Budde U, Oyen F et al (2003) Von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP. Blood 101:1845–1850

    Article  CAS  PubMed  Google Scholar 

  • Sutor AH (1995) Thrombocytosis in childhood. Semin Thromb Hemost 21:330–339

    Article  CAS  PubMed  Google Scholar 

  • Triplett DA (1998) Many faces of lupus anticoagulants. Lupus 7(Suppl 2):18–22

    Article  Google Scholar 

  • Tuddenham EG, Pemberton S, Cooper DN (1995) Inherited factor VII deficiency: genetics and molecular pathology. Thromb Haemost 74:313–321

    CAS  PubMed  Google Scholar 

  • Wood AJJ (1998) Thrombopoietin. N Engl J Med 339:746–754

    Article  Google Scholar 

  • Zimmerman TS, Ratnoff OD, Powell AE (1971) Immunologic differentiation of classic hemophilia (factor 8 deficiency) and von Willebrand’s dissase, with observations on combined deficiencies of antihemophilic factor and proaccelerin (factor V) and on an acquired circulating anticoagulant against antihemophilic factor. J Clin Invest 50:244–254

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Pädiatrische Hämatologie und Onkologie, Martinistr. 52, 20246, Hamburg, Deutschland

    R. Schneppenheim

  2. MVZ Wagnerstibbe, Amedes-Gruppe, Gerinnungslabor, Georgstr. 50, 30159, Hannover, Deutschland

    F. Bergmann

Authors
  1. R. Schneppenheim
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  2. F. Bergmann
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Corresponding author

Correspondence to R. Schneppenheim .

Editor information

Editors and Affiliations

  1. Universität Heidelberg, Zentrum für Kinder- und Jugendmedizin, Heidelberg, Germany

    Georg F. Hoffmann

  2. Zentrum für Kinderheilkunde, Bonn, Germany

    Michael J. Lentze

  3. Sinzheim, Germany

    Jürgen Spranger

  4. Universitätsmedizin Mainz Zentrum für Kinder- und Jugendmediz, Mainz, Germany

    Fred Zepp

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Schneppenheim, R., Bergmann, F. (2016). Erworbene Koagulopathien bei Kindern und Jugendlichen. In: Hoffmann, G., Lentze, M., Spranger, J., Zepp, F. (eds) Pädiatrie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54671-6_222-1

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  • DOI: https://doi.org/10.1007/978-3-642-54671-6_222-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-54671-6

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Chapter history

  1. Latest

    Erworbene Koagulopathien bei Kindern und Jugendlichen
    Published:
    29 January 2020

    DOI: https://doi.org/10.1007/978-3-642-54671-6_222-2

  2. Original

    Erworbene Koagulopathien bei Kindern und Jugendlichen
    Published:
    05 April 2016

    DOI: https://doi.org/10.1007/978-3-642-54671-6_222-1

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