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Default Factors in Quantitative Risk Assessment

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Regulatory Toxicology

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Abstract

Only rarely is sufficient toxicological knowledge available on a risk of interest. In cases where toxicological data are incomplete for a specific quantitative risk assessment, the assessment may also draw on general scientific knowledge gained from experience with other chemical substances. However, this approach of extrapolation, using default factors based on empirical evidence, is not without controversy.

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Author information

Authors and Affiliations

  1. Forschungs- und Beratungsinstitut Gefahrstoffe GmbH, Freiburg, Germany

    Klaus Schneider

  2. School of Environmental Sciences, University of Guelph, Guelph, ON, Canada

    Leonard Ritter

Authors
  1. Klaus Schneider
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  2. Leonard Ritter
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Corresponding author

Correspondence to Klaus Schneider .

Editor information

Editors and Affiliations

  1. Universität München Inst. Pharmakologie und Toxikologie, München, Germany

    Franz-Xaver Reichl

  2. Tübingen, Germany

    Michael Schwenk

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Schneider, K., Ritter, L. (2021). Default Factors in Quantitative Risk Assessment. In: Reichl, FX., Schwenk, M. (eds) Regulatory Toxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36206-4_59-2

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  • DOI: https://doi.org/10.1007/978-3-642-36206-4_59-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-36206-4

  • Online ISBN: 978-3-642-36206-4

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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