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Alexia, Without Agraphia

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Encyclopedia of Ophthalmology
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Synonyms

Disconnection syndrome; Pure alexia; Pure word blindness; Word blindness

Definition

Alexia without agraphia is an acquired inability to comprehend written language as a consequence of brain damage. It is a disorder of written language. A specialized variety of aphasia, this term alexia without agraphia refers to a specific disability in reading where the ability to write is preserved. There may be intact auditory and verbal aspects of language but there is a loss of efficient reading despite adequate visual acuity. It was first described by Dejerine in a patient with an associated incomplete right homonymous hemianopia from a lesion of the left fusiform and lingual gyri. The left angular gyrus stores the visual representation of words (needed for reading and writing), and a disconnection of the visual inputs crossing in the splenium of the corpus callosum of one hemisphere (typically the intact right occipital lobe) from the left angular gyrus could disrupt reading but leave...

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Further Reading

  • Cohen L, Martinaud O, Lemer C, Lehericy S, Samson Y, Obadia M, Slachevsky A, Dehaene S (2003) Visual word recognition in the left and right hemispheres: anatomical and functional correlates of peripheral alexias. Cereb Cortex 13(12):1313–1333

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  • Daniel MS, Bolter JF, Long CJ (1992) Remediation of alexia without agraphia: a case study. Brain Inj 6(6):529–542

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  • Leff AP, Scott SK, Crewes H, Hodgson TL, Cowey A, Howard D, Wise RJS (2000) Impaired reading in patients with right hemianopia. Ann Neurol 47:171–178

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  • Marsh EB, Hillis AE (2005) Cognitive and neural mechanisms underlying reading and naming: evidence from letter-by-letter reading and optic aphasia. Neurocase 11:325–337

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  • Pure alexia (letter-by-letter reading). (1998) Cogn Neuropsychol 15(1/2): Special issue

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Correspondence to Andrew G. Lee .

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Al-Zubidi, N., Lee, A.G. (2015). Alexia, Without Agraphia. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_967-1

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_967-1

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  • Online ISBN: 978-3-642-35951-4

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