Synonyms
Definition
Corneal pigmentation refers to discoloration of the cornea at any of its layers.
Etiology
Pigmentations of the cornea may occur with or without ocular or systemic disease (Biswell 2011). Multiple different forms of corneal pigmentation may be encountered; the most common etiologies include local or systemic exposure to metals and medications. Deposition may occur anteriorly from the tear film, peripherally through vasculature (in arcus), or posteriorly (through the aqueous) (Naumann and Apple 1986; Khurana 2007; Biswell 2011).
Occurrence
Iron deposition: iron deposition in the cornea may occur in significant quantity to become clinically visible. This generally involves epithelial uptake of iron from the tear film and therefore correlates with lid position and tear film stasis on the ocular surface (Khurana 2007; Biswell 2011).
The Hudson-Stahli lineis a horizontal line of deposited iron in the corneal epithelium at the junction of the upper...
References
Biswell R (2011) Vaughan & Asbury’s general ophthalmology, vol 16, 18th edn. McGraw-Hill, New York, pp 692–695
Khurana AK (2007) Comprehensive ophthalmology, vol 9, 4th edn. New Age International, New Delhi, p 234
Naumann G, Apple D (1986) Pathology of the eye, vols 7 and 15, 1st edn. Springer-Verlag, New York, pp 386–309, 877
Smolin G et al (2005) The cornea: Scientific foundations and clinical practice, vol 48, 4th edn. Lippincott Williams & Williams, Philadelphia, p 879
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Garrett, B., Eghrari, A.O. (2014). Corneal Pigmentations. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_940-1
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DOI: https://doi.org/10.1007/978-3-642-35951-4_940-1
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