Paracentral areas of the cornea in keratoconus
Peripheral thinning spherically in keratoglobus
Inferior and peripheral regions of the cornea in pellucid marginal degeneration
Keratoconus is the most common corneal dystrophy/degeneration, while keratoglobus is rare. These degenerations are typically diagnosed in the second decade of life and progress into the third and fourth decades. Pellucid marginal degeneration is very rare.
Male and female distribution is roughly equal.
Patients with stromal degenerations can present both with stable and decreasing vision. Rarely, these patients may present with acute onset of pain and blurry vision in the setting of acute hydrops resulting from a break in Descemet’s membrane.
Patients also sometimes complain of “ghost” images,...