Encyclopedia of Ophthalmology

Living Edition
| Editors: Ursula Schmidt-Erfurth, Thomas Kohnen

Stromal Degenerations

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35951-4_931-1

Synonyms

Definition

Stromal degenerations of the cornea are characterized by bilateral, progressive thinning of the cornea.
  1. 1.

    Paracentral areas of the cornea in keratoconus

     
  2. 2.

    Peripheral thinning spherically in keratoglobus

     
  3. 3.

    Inferior and peripheral regions of the cornea in pellucid marginal degeneration

     

Epidemiology

Keratoconus is the most common corneal dystrophy/degeneration, while keratoglobus is rare. These degenerations are typically diagnosed in the second decade of life and progress into the third and fourth decades. Pellucid marginal degeneration is very rare.

Male and female distribution is roughly equal.

History

Patients with stromal degenerations can present both with stable and decreasing vision. Rarely, these patients may present with acute onset of pain and blurry vision in the setting of acute hydrops resulting from a break in Descemet’s membrane.

Patients also sometimes complain of “ghost” images,...

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Further Reading

  1. (2013) Basic and clinical science course 2013–2014 section 8 external disease and cornea. Amer Academy of Ophthalmology. PrintGoogle Scholar
  2. Lang GK, Gareis O (2007) Ophthalmology: a pocket textbook atlas. Thieme, StuttgartGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.University of Florida – JacksonvilleJacksonvilleUSA