Skip to main content
SpringerLink
Log in

Intraocular Injection of Ocular Drugs

  • Living reference work entry
  • First Online:
Encyclopedia of Ophthalmology

  • 17 Accesses

Indications

Intraocular injections are the fastest growing procedure in ophthalmology. They are commonly used for the treatment age-related macular degeneration (bevacizumab, ranibizumab), iris neovascularization secondary to proliferative diabetic retinopathy (bevacizumab), and macular edema (bevacizumab and triamcinolone acetonide) due to diabetic retinopathy, vein occlusion, or uveitis.

In addition intravitreal methotrexate has been used to treat intraocular lymphoma associated with primary central nervous system lymphoma. Less commonly it has been used in patients with uveitis and advanced proliferative diabetic retinopathy.

Adverse Effects

Intravitreal injections often lead to increased intraocular pressure (IOP) immediately after the procedure. In 2008, Kim et al. demonstrated that eyes injected with ranibizumab, bevacizumab, pegaptanib, and triamcinolone acetonide had transient IOP spikes immediately after the procedure. However, close monitoring is necessary especially in...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Vanderbilt University Medical Center, Vanderbilt Eye Institute, 2311 Pierce Avenue, Nashville, TN, 37232, USA

    Laura L. Wayman

Authors
  1. Laura L. Wayman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Laura L. Wayman .

Editor information

Editors and Affiliations

  1. Dept of Ophthal & Optometry,AKH, Medical University of Wien Dept of Ophthal & Optometry,AKH, Wien, Austria

    Ursula Schmidt-Erfurth

  2. Department of Ophthalmology, Goethe University of Frankfurt am Main Department of Ophthalmology, Frankfurt am Main, Germany

    Thomas Kohnen

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Wayman, L.L. (2012). Intraocular Injection of Ocular Drugs. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_81-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-35951-4_81-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation