Definition
Inflammation of the conjunctiva caused by Neisseria gonorrhoeae infection.
Etiology
Gonococcal conjunctivitis may be acquired through direct genital-eye transmission, genital-hand-eye contact, or maternal-neonate transmission during vaginal delivery.
Clinical Presentation
Gonococcal conjunctivitis is characterized by hyperacute onset of purulent exudates, conjunctival chemosis and hyperemia, and eyelid swelling. It may also be associated with the formation of membranes and preauricular lymphadenopathy. Keratitis is the most frequent cause of sight-threatening complication and occurs in 15–40 % of cases.
Notable signs of corneal involvement include marginal infiltrates, epithelial haze, epithelial defects, and peripheral infectious keratitis. If left untreated, keratitis may progress to ulceration and eventually perforation.
In neonates, symptoms are typically bilateral and begin within 2–5 days after parturition.
Diagnosis
In cases of neonatal gonococcal conjunctivitis, a...
Further Reading
Albert et al (1994) Albert & Jakobiec principles and practice of ophthalmology. (4) 2827–2829
American Academy of Pediatrics (2009) Gonococcal infections. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS (eds) Red book: report of the Committee on Infectious Diseases, 28th edn. American Academy of Pediatrics, Elk Grove Village, pp 305–313
Centers for Disease Control and Prevention, Workowski KA, Berman SM (2006) Sexually transmitted diseases treatment guidelines 2006. MMWR Recomm Rep 55(RR- 11):1–94
Laga M, Plummer F, Piot P et al (1988) Prophylaxis of gonococcal and chlamydial ophthalmia neonatorum. N Engl J Med 318:653–657
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Srinagesh, V. (2014). Gonococcal Conjunctivitis. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_728-1
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DOI: https://doi.org/10.1007/978-3-642-35951-4_728-1
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