Skip to main content

Cavernous Sinus Syndrome

  • Living reference work entry
  • First Online:
Encyclopedia of Ophthalmology

Synonyms

Jefferson syndrome

Definition

Cavernous sinus syndrome (CSS) is defined by signs and symptoms (see cavernous sinus anatomy) related to cavernous sinus pathology and include cranial neuropathies, ophthalmoplegia, proptosis and orbital congestion, orbital or facial pain, trigeminal sensory loss, and ocular sympathetic disturbance such as Horner syndrome. CSS can be caused by multiple conditions resulting in pathology of the cavernous sinus or the structures within. CSS can be divided into four types based on etiology: infection, noninfectious inflammation, vascular lesion, and neoplasm. Infectious diseases include cavernous sinus thrombophlebitis, actinomycosis, rhinocerebral mucormycosis, and aspergillosis. Noninfectious inflammatory conditions include Tolosa-Hunt syndrome and idiopathic or secondary inflammatory syndromes. Different types of CSS vascular lesions include aneurysm of the internal carotid artery (ICA), carotid-cavernous fistula, and dural arteriovenous fistula....

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Bone I, Hadley DM (2005) Syndromes of the orbital fissure, cavernous sinus, cerebellopontine angle, and skull base. J Neurol Neurosurg Psychiatry 76(Suppl 3):iii29–iii38

    PubMed  PubMed Central  Google Scholar 

  • Kline LB, Hoyt WF (2001) The Tolosa-Hunt syndrome. J Neurol Neurosurg Psychiatry 71(5):577–582

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lee JH, Lee HK, Park JK, Choi CG, Suh DC (2003) Cavernous sinus syndrome: clinical features and differential diagnosis with MR imaging. AJR Am J Roentgenol 181(2):583–590

    Article  PubMed  Google Scholar 

  • Longo DL et al (eds) (2012) Harrison’s principles of internal medicine, 18th edn. McGraw Hill, New York, p 2438

    Google Scholar 

  • Ropper AH, Samuels MA (2009) Adam and Victor’s principles of neurology, 9th edn. McGraw Hill, New York, pp 605–749

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Andrew G. Lee .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg (outside the USA)

About this entry

Cite this entry

Chen, Y., Morgan, M.L., Palau, A.E.B., Almarzouqi, S.J., Lee, A.G. (2015). Cavernous Sinus Syndrome. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_535-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-35951-4_535-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics