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Encyclopedia of Ophthalmology pp 1–3Cite as

Pigmentary Glaucoma

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Synonyms

Glaucoma associated with pigment dispersion syndrome (PDS)

Definition

Secondary open-angle glaucoma associated with PDS, an autosomal dominant disorder, in which irido-zonular friction disrupts the iris pigment epithelium dispersing pigment granules throughout the anterior chamber.

Etiology

The underlying condition, PDS, can be explained by the anatomical phenomenon of posterior iris concavity, caused by reverse pupillary block due to increased irido-lenticular contact and physiological events such as blinking and exercise. Increased aqueous pressure in the anterior chamber promotes a backward bowing of the iris and mechanical rubbing against the zonular fibers of the lens leading to liberation of iris pigment. PDS is believed to be strongly influenced by genetic background with linkage to chromosomal locations 7q35-36 and 18q22.

Clinical Presentation

PDS is a bilateral disorder. Key features are the dispersion and accumulation of pigment on anterior segment structures such as...

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References

  • Anderson MG (2010) Pigmentary dispersion syndrome and glaucoma. In: Levin LA, Albert DM (eds) Ocular disease: mechanisms and management. Elsevier, Amsterdam, pp 165–170

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  • Niyadurupola N, Broadway DC (2008) Pigment dispersion syndrome and pigmentary glaucoma – a major review. Clin Exp Ophthalmol 36:868–882

    Article  PubMed  Google Scholar 

  • Ritch R (2010) Pigment dispersion syndrome and pigmentary glaucoma. In: Dartt DA, Besharse JC, Dana R (eds) Encyclopedia of the eye, vol 3. Academic, Oxford, pp 451–460

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Author information

Authors and Affiliations

  1. Universität Erlangen-Nürnberg, Augenklinik mit Poliklinik, Schwabachanlage 6, 91054, Erlangen, Germany

    Ursula Schlötzer-Schrehardt

Authors
  1. Ursula Schlötzer-Schrehardt
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Corresponding author

Correspondence to Ursula Schlötzer-Schrehardt .

Editor information

Editors and Affiliations

  1. Dept of Ophthal & Optometry,AKH, Medical University of Wien Dept of Ophthal & Optometry,AKH, Wien, Austria

    Ursula Schmidt-Erfurth

  2. Department of Ophthalmology, Goethe University of Frankfurt am Main Department of Ophthalmology, Frankfurt am Main, Germany

    Thomas Kohnen

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Schlötzer-Schrehardt, U. (2016). Pigmentary Glaucoma. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_301-3

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_301-3

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-35951-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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