Cutaneous Horn+B2658

Synonyms

Cutaneous horn; Hyperkeratosis

Definition

A lesion with extensive hyperkeratosis projecting in a protruding, sometimes conoid, manner.

Etiology

Thickening of the keratin layer from the base of a proliferative lesion, results in a cutaneous horn. The base lesion may be a benign, premalignant, or malignant lesion.

Clinical Presentation

Present as hyperkeratotic papules that protrude from the skin, usually several millimeters in height. They are more common in sun exposed areas.

Diagnostics

Biopsy of the base of the lesion is required to determine if malignancy is present. The majority of lesions are benign, but 20 % of lesions may be premalignant or malignant (Albert and Jakobiec 2008).

Differential Diagnosis

• Actinic keratosis

• Squamous cell carcinoma

• Seborrheic keratosis

• Verruca vulgaris

• Basal cell carcinoma

Prophylaxis

Sun exposure and UV protection may be recommended, based on the type of lesion at the base of the cutaneous horn.

Therapy

Biopsy of the base of the lesion is...