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Punctate Inner Choroidopathy

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Encyclopedia of Ophthalmology
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Introduction

Punctate inner choroidopathy is an uncommon posterior multifocal chorioretinopathy first described by (Watzke et al. 1984). It is characterized by the presence of small, focal, yellow lesions at the posterior pole occurring at the level of the inner choroid/retinal pigment epithelium in the absence of vitreous inflammation. It usually affects young, myopic females (who may also be fair haired with blue- or light-colored irides).

The usual presenting symptoms include blurred vision, scotomata, and/or photopsia. These usually occur due secondary to inflammatory foci at the time of presentation, but can be caused by choroidal neovascularization (CNV) complicating the inflammatory focus or by scarring consequent to the inflammation.

Despite having such a distinct clinical phenotype, there remains some controversy as to whether this disease simply represents part of a larger spectrum of chorioretinal disorders of unknown origin, including idiopathic multifocal choroiditis...

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References

  • Atan D, Fraser-Bell S, Plskova J, Kuffova L, Hogan A, Tufail A et al (2011) Punctate inner choroidopathy and multifocal choroiditis with panuveitis share haplotypic associations with IL10 and TNF loci. Invest Ophthalmol Vis Sci 52(6):3573–3581

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Menezo, V., Taylor, S.R.J. (2015). Punctate Inner Choroidopathy. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_1053-1

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  • DOI: https://doi.org/10.1007/978-3-642-35951-4_1053-1

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  • Online ISBN: 978-3-642-35951-4

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