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The Prokaryotes pp 267–285Cite as

Aerobic Methylotrophic Prokaryotes

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Abstract

This chapter describes biochemical pathways operating in aerobic methylotrophic bacteria. We first define aerobic methylotrophy as a specific metabolic capability and describe the phylogenetic diversity of these bacteria. We then describe enzymes involved in primary oxidation of different single carbon substrates, resulting in formaldehyde or methyl or methylene radical, and describe the variety of pathways used for their assimilation and dissimilation. We also give a brief account of genetic manipulation tools in methylotrophic bacteria and examples of systems approaches for studying their metabolism, including availability of whole genome sequence information.

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Authors and Affiliations

  1. Department of Chemical Engineering, University of Washington, Seattle, WA, USA

    Ludmila Chistoserdova

  2. Department of Chemical Engineering and Department of Microbiology, University of Washington, 357242, Seattle, WA, 98195-7242, USA

    Prof. Mary E. Lidstrom

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  1. Ludmila Chistoserdova
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Correspondence to Ludmila Chistoserdova .

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  1. Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel

    Eugene Rosenberg

  2. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA

    Edward F. DeLong

  3. Department of Microbiology and Immunology, Harvard Medical School, Boston, MA, USA

    Stephen Lory

  4. Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany

    Erko Stackebrandt

  5. Laboratory of Microbiology, Institute of Biology, Center for Health Sciences, Federal University of Rio de Janeiro (UFRJ), Ilha do Fundão, Rio de Janeiro, Brazil

    Fabiano Thompson

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Chistoserdova, L., Lidstrom, M.E. (2013). Aerobic Methylotrophic Prokaryotes. In: Rosenberg, E., DeLong, E.F., Lory, S., Stackebrandt, E., Thompson, F. (eds) The Prokaryotes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-30141-4_68

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