Definition
Chemotherapy is defined as the use of chemical agents for treatment. Chemotherapy as used for cancer generally refers to small molecules that damage proliferating cells. It represents systemic treatment in contrast to radiotherapy and surgery that represent local treatment. Classes of systemic agents may also include hormones, cytokines, and antitumor vaccines.
http://www.chemocare.com/whatis/important_chemotherapy_terms.asp
Characteristics
The Challenge
Cancer is the most feared, morbid, and mortal of diseases. In the USA, five million people contract cancer per year, of whom one third, or almost half a million citizens, will die of their disease. Most cancers start in a specific location (e.g., breast, lung) and spread to regional lymph nodes; in breast cancer, spread is to the armpit and subsequent dissemination by the bloodstream to distant organs. For cancers that are diagnosed before such dissemination, local treatment with surgery and/or radiotherapy may be curative....
References
Fearon ER, Vogelstein B (2000) Tumor suppressor gene defects in human cancer. Cancer Med 5:67–87
Holland JF, Frei E III, Kufe DW et al (2000) Principles of medical oncology. Cancer Med 5:503–510
Pollock RE, Morton DL (2000) Principles of medical oncology. Cancer Med 5:448–458
Ries LAG, Kosary CL, Hankey BF et al (eds) (1999) SEER cancer statistics review 1973–1996. National Cancer Institute, Bethesda
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Frei, E. (2015). Chemotherapy. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_1083-2
Download citation
DOI: https://doi.org/10.1007/978-3-642-27841-9_1083-2
Received:
Accepted:
Published:
Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-27841-9
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences