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Crohn’s Disease: Minimizing Radiation Dose

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Abdominal Imaging

Abstract

There is increasing awareness of high cumulative ionizing radiation exposure in patients with Crohn’s disease (CD). We outline the principle causes for concern and the subgroups of Crohn’s patients at risk of greatest cumulative dose. We present a practical approach to radiation dose reduction in Crohn’s patients with a focus on evolving CT Technology. This chapter will inform the reader why radiation dose should be reduced in CD patients and will indicate how this task can be approached in clinical practice.

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References

  • Allen BC, et al. Effect of altering automatic exposure control settings and quality reference mAs on radiation dose, image quality, and diagnostic efficacy in MDCT enterography of active inflammatory Crohn’s disease. AJR Am J Roentgenol. 2010;195(1):89–100.

    Article  PubMed  Google Scholar 

  • Berrington de González A, Mahesh M, Kim KP, et al. Projected cancer risks from computed tomographic scans performed in the United States in 2007. Arch Intern Med. 2009;169:2071–7.

    Article  PubMed  Google Scholar 

  • Boedeker KL, McNitt-Gray MF. Application of the noise power spectrum in modern diagnostic MDCT. Part II. Noise power spectra and signal to noise. Phys Med Biol. 2007;52:4047–61.

    Article  PubMed  CAS  Google Scholar 

  • Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C, et al. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks. Radiat Res. 2007;167:396–416.

    Article  PubMed  CAS  Google Scholar 

  • Coakley FV, Gould R, Yeh BM, Arenson RL. CT radiation dose: what can you do right now in your practice? AJR Am J Roentgenol. 2011;196(3):619–25.

    Article  PubMed  Google Scholar 

  • Council Directive 97/43/Euratom of 30 June 1997 on health protection of individuals against the dangers of ionizing radiation in relation to medical exposure, and repealing Directive 84/466/Euratom. Off J Eur Communities. L180:0022–0027; 1997.

    Google Scholar 

  • Desmond AN, O’Regan K, Curran C, McWilliams S, Fitzgerald T, Maher MM, et al. Crohn’s disease: factors associated with exposure to high levels of diagnostic radiation. Gut. 2008;57:1524–9.

    Article  PubMed  CAS  Google Scholar 

  • Dougeni E, et al. A review of patient dose and optimisation methods in adult and paediatric CT scanning. Eur J Radiol. 2011 (epub ahead of press).

    Google Scholar 

  • Flicek KT, Hara AK, Silva AC, Wu Q, Peter MB, Johnson CD. Reducing the radiation dose for CT colonography using adaptive statistical iterative reconstruction: a pilot study. AJR Am J Roentgenol. 2010;195:126–31.

    Article  PubMed  Google Scholar 

  • Freeman HJ. Colorectal cancer risk in Crohn’s disease. World J Gastroenterol. 2008;14(12):1810–11.

    Article  PubMed  Google Scholar 

  • Hara AK, Paden RG, Silva AC, Kujak JL, Lawder HJ, Pavlicek W. Iterative reconstruction technique for reducing body radiation dose at CT: feasibility study. AJR Am J Roentgenol. 2009;193:764–71.

    Article  PubMed  Google Scholar 

  • Herfarth H, Palmer L. Risk of radiation and choice of imaging. Dig Dis. 2009;27:278–84.

    Article  PubMed  Google Scholar 

  • Kalra MK, Wittram C, Maher MM, Sharma A, Avinash GB, Karau K, et al. Can noise reduction filters improve low-radiation-dose chest CT images? Pilot study. Radiology. 2003;228:257–64.

    Article  PubMed  Google Scholar 

  • Kalra MK, Maher MM, Toth TL, Kamath RS, Halpern EF, Saini S. Comparison of Z-axis automatic tube current modulation technique with fixed tube current CT scanning of abdomen and pelvis. Radiology. 2004a;232:347–53.

    Article  PubMed  Google Scholar 

  • Kalra MK, Maher MM, Toth TL, Kamath RS, Halpern EF, Saini S. Radiation from “extra” images acquired with abdominal and/or pelvic CT: effect of automatic tube current modulation. Radiology. 2004b;232:409–14.

    Article  PubMed  Google Scholar 

  • Kambadakone AR, Prakash P, Hahn PF, Sahani DV. Low-dose CT examinations in Crohn’s disease: impact on image quality, diagnostic performance, and radiation dose. AJR Am J Roentgenol. 2010;195(1):78–88.

    Article  PubMed  Google Scholar 

  • Kambadakone AR, et al. Low-dose MDCT and CT enterography of patients with Crohn disease: feasibility of adaptive statistical iterative reconstruction. AJR Am J Roentgenol. 2011;196(6):W743–52.

    Article  PubMed  Google Scholar 

  • Koller CJ, Eatough JP, Bettridge A. Variations in radiation dose between the same model of multislice CT scanner at different hospitals. Br J Radiol. 2003;76(911):798–802.

    Article  PubMed  CAS  Google Scholar 

  • Lee CL, Haims AH, Monico EP, Brink JA, Forman HP. Diagnostic CT scans: assessment of patient, physician, and radiologist awareness of radiation dose and possible risks. Radiology. 2004;231:393–8.

    Article  PubMed  Google Scholar 

  • May MS, Wüst W, Brand M, Stahl C, Allmendinger T, Schmidt B, Uder M, et al. Dose reduction in abdominal computed tomography: intraindividual comparison of image quality of full-dose standard and half-dose iterative reconstructions with dual-source computed tomography. Invest Radiol. 2011;46(7):465–70.

    Article  PubMed  Google Scholar 

  • O’Sullivan J, O’Connor OJ, O’Regan K, Clarke B, Burgoyne LN, Ryan MF, et al. An assessment of medical students’ awareness of radiation exposures associated with diagnostic imaging investigations. Insight Imaging. 2010;1:86–92.

    Article  Google Scholar 

  • Silva AC, Lawder HJ, Hara A, Kujak J, Pavlicek W. Innovations in CT dose reduction strategy: application of the adaptive statistical iterative reconstruction algorithm. AJR Am J Roentgenol. 2010;194:191–9.

    Article  PubMed  Google Scholar 

  • Singh S, et al. Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques. Radiology. 2010;257(2):373–83.

    Article  PubMed  Google Scholar 

  • Strauss KJ, Goske MJ, Kaste SC, Bulas D, Frush DP, Butler P, et al. Image gently: ten steps you can take to optimize image quality and lower CT dose for pediatric patients. AJR Am J Roentgenol. 2010;194:868–73.

    Article  PubMed  Google Scholar 

  • Winklehner A, Karlo C, Puippe G, Schmidt B, Flohr T, Goetti R, Pfammatter T, et al. Raw data-based iterative reconstruction in body CTA: evaluation of radiation dose saving potential. Eur Radiol. 2011;21(12):2521–6.

    Article  PubMed  Google Scholar 

  • Yadava G, Kulkarni S, Rodriguez Colon Z, Thibault J, Hsieh J. TU-A-201B-03: dose reduction and image quality benefits using model based iterative reconstruction (MBIR) technique for computed tomography. Med Phys. 2010;37:3372. doi:10.1118/1.3469177.

    Article  Google Scholar 

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Correspondence to Michael Maher .

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McLaughlin, P., O’Neill, S.B., O’Connor, O.J., Shanahan, F., Maher, M. (2013). Crohn’s Disease: Minimizing Radiation Dose. In: Hamm, B., Ros, P.R. (eds) Abdominal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-13327-5_219

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  • DOI: https://doi.org/10.1007/978-3-642-13327-5_219

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-13326-8

  • Online ISBN: 978-3-642-13327-5

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