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Renal Dysplasia/Hypoplasia

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Pediatric Nephrology

Abstract

During normal kidney development, interactions between the branching ureteric bud (UB) and the metanephric mesenchyme (M) generate all the nephrons of each kidney by about the 8th month of gestation. Nephrons are attached like apples to branches of the arborized collecting system. At birth, this crop of nephrons constitutes the individual’s nephron endowment for life and ranges widely among normal humans from 0.3 to 1.1 million nephrons per kidney (1).

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Authors and Affiliations

  1. Division of Pediatric Nephrology, Montreal Children’s Hospital, Montreal, QC, Canada

    Paul Goodyer

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  1. Paul Goodyer
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Editors and Affiliations

  1. Medical College of Wisconsin, Wisconsin, USA

    Ellis Avner (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology) (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology)

  2. Harvard Medical School, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA

    William Harmon (Professor of Pediatrics, Director, Pediatric Nephrology) (Professor of Pediatrics, Director, Pediatric Nephrology)

  3. Service de Néphrologie Pédiatrique Centre de référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), Hôpital Necker‐Enfants Malades, 149, rue de Sèvres, 75743, Paris Cedex 15, France

    Patrick Niaudet

  4. Department of Pediatrics Wakayama Medical University, Wakayama Medical University Hospital, 641–8510811–1, Kimiidera, Wakayama City, Japan

    Norishige Yoshikawa (Professor and Chair Pediatrician‐in‐Chief) (Professor and Chair Pediatrician‐in‐Chief)

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© 2009 Springer-Verlag Berlin Heidelberg

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Goodyer, P. (2009). Renal Dysplasia/Hypoplasia. In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76341-3_5

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  • DOI: https://doi.org/10.1007/978-3-540-76341-3_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76327-7

  • Online ISBN: 978-3-540-76341-3

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