Addiction is the aberrant use of a substance in a manner characterized by: 1) loss of control over medication use, 2) compulsive use, 3) continued use despite physical, psychological or social harm, and 4) craving, often obtaining supply by deceptive or illegal means. This syndrome also includes a great deal of time used to obtain the medication, use the medication, or recover from its effects. Addiction is not the same as tolerance or dependence. Unlike the other two, which are physiological responses, addiction implies drug seeking behaviors and has a host of psychological factors. Addiction is rare among patients given opioids for the treatment of pain.