Definition
The principal primary active transport system in neurons, the Na/K-ATPase utilizes energy to maintain cation cellular concentrations by extruding Na and accumulating K ions, thus creating an electrical potential across the neuronal cell membrane. It is estimated that 25 to 40% of brain energy utilization may be related to Na/K-ATPase activity. Abnormalities in the pump may lead to neuronal dysfunction, although the exact relationship to familial hemiplegic migraine is not known.
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© 2007 Springer-Verlag Berlin Heidelberg
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(2007). ATP-Dependent Na+/K+ Pump. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_312
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DOI: https://doi.org/10.1007/978-3-540-29805-2_312
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-43957-8
Online ISBN: 978-3-540-29805-2
eBook Packages: MedicineReference Module Medicine