Arthritis Model, Osteoarthritis
Degenerative Joint Disease; Arthritis; Osteoarthritis Model
Osteoarthritis (OA) and other degenerative joint diseases affect almost one third of all adults, equaling nearly 70 million adults in the United States and 34 million adults in Europe. It is the leading cause of disability in the United States. The most important risk factor for OA is age (Elders 2000), and as the aging population is dramatically increasing, the prevalence of the disease is likewise expected to increase. OA is distinct from rheumatoid arthritis, which is a systemic inflammatory disease, and is much less prevalent.
OA is frequently associated with severe pain, but the sources of this pain are not fully understood, which has presented many obstacles for its treatment and...
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