Encyclopedia of Pain

2007 Edition

Antidromic Activation/Invasion

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29805-2_250

Definition

Eliciting action potentials in the axon of a neuron, which propagate toward the cell body to invade the soma and the dendrites, in an opposite direction to that observed when the neurons are naturally excited (orthodromic direction). The stimulation of an axonal ending triggers a potential that is conveyed in the antidromic direction. The recognition of an antidromic potential on three criterion (latency stability, ability to follow high frequency stimulation, and observation of collision between orthodromic and antidromic potential) permitted the identification of one projection of a recorded neuron.

 Corticothalamic and Thalamocortical Interactions

 Nociceptor, Fatigue

 Nociceptors in the Orofacial Region (Temporomandibular Joint and Masseter Muscle)

 Parabrachial Hypothalamic and Amydaloid Projections

 Spinohypothalamic Tract, Anatomical Organization and Response Properties

  Spinothalamic Neuron

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© Springer-Verlag Berlin Heidelberg 2007