Encyclopedia of Pain

2007 Edition

AMPA Glutamate Receptor (AMPA Receptor)

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29805-2_186


A type of ionotropic glutamate receptor that is activated by the specific agonist alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA). AMPA receptors comprise of several subunits (GluR1, GluR2, GluR3, GluR4) that form a heteromeric receptor-ion-channel complex, the composition of which affects the kinetic properties of the receptor-ion-channel. AMPA receptors mediate the majority of fast synaptic transmission in the central nervous system.

 Metabotropic Glutamate Receptors in the Thalamus

 Nociceptive Neurotransmission in the Thalamus

 Opiates During Development

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© Springer-Verlag Berlin Heidelberg 2007