Encyclopedia of Pain

2007 Edition

Amitriptyline

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29805-2_185

Definition

A tricyclic antidepressant drug utilized for the treatment of chronic pain, particularly effective in the craniofacial region. Its antinociceptive effect is independent of its antidepressive activity. Amitriptyline controls chronic facial pain in a relatively low dose (10–25 mg/day), and is also used as a prophylactic drug for migraine.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2007