Encyclopedia of Pain

2007 Edition


Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29805-2_185


A tricyclic antidepressant drug utilized for the treatment of chronic pain, particularly effective in the craniofacial region. Its antinociceptive effect is independent of its antidepressive activity. Amitriptyline controls chronic facial pain in a relatively low dose (10–25 mg/day), and is also used as a prophylactic drug for migraine.

 Atypical Facial Pain, Etiology, Pathogenesis and Management

 Fibromyalgia, Mechanisms and Treatment

 Migraine, Preventive Therapy

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© Springer-Verlag Berlin Heidelberg 2007