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Table 9 Strong recommendations from CDC regarding prevention of SSI

From: Nosocomial Infections and Ventilator-Associated Pneumonia in Cancer Patients

Bath with water and soap on the night prior to surgery

Administer AMP ONLY IF indicated, and AMP to be administered in the correct time and correct dose such that optimal bactericidal concentration of the agents is established in the serum and tissues when the incision is made

Administer AMP for all caesarean section procedures

Use an alcohol-based antiseptic agent for surgical site preparation unless otherwise specified

Avoid application of all antimicrobial agents including ointments, solutions, or powders to the surgical incision

Use of antibiotic (triclosan)-coated sutures

Strict glycemic control in the perioperative period with target blood glucose levels less than 200 mg/dL in all patients irrespective of diabetic status

Maintain perioperative normothermia

Optimize tissue oxygenation by maintaining normothermia and euvolumia

Provide an increased Fio2 during surgery and in the immediate postoperative period after extubation

Transfuse blood and blood products as per transfusion thresholds

Avoid additional AMP after closure of the surgical incision in the operating room

  1. CDC Centre for Disease Control and Prevention, AMP antimicrobial prophylaxis