Abstract
Approximately half million women developed cervical cancer each year, and half of this number die as a result of this diseases each year. Eighty percent of the burden of cervical cancer occurs in developing countries with no prevention and screening cancer programs. Almost all cases of cervical cancer develop secondary to infection with human papillomavirus (HPV) which does affect 80% of sexually active women at one stage. HPV is the most common sexually transmitted infection (STI). Most women who get the HPV infection will clear the infection by themselves; however, the infection might persist in few women. It is the persistent high-risk HPV infection (mainly HPV 16 and 18) which caused cervical cancer. There are 14,280 new cases of cervical cancer in the Arab region in 2018 with 9,354 deaths. There is no single strategy that can be applied across all Arab countries due to variations in resource, demography, and the burden of cervical cancer in each country. Arab countries with high resources can adopt both organized screening program and HPV vaccination; however, in low-resource Arab countries, HPV vaccination in collaboration with funding agencies such as Gavi allies might be the best cervical cancer intervention strategy.
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References
Al Sairafi M, Mohamed F (2009) Knowledge, attitudes, and practice related to cervical l cancer screening among Kuwaiti women. Med Princ Pract 18(1):35–42
Al Zaabi M, Al Muqbali S, Al Sayadi T, Al Ameeri S, Ortashi O (2015) Age specific cytological abnormalities in women screened for cervical Cancer in the Emirate of Abu Dhabi. Asian Pac J Cancer Prev 16(15):6375–6379
Alemany L (2015) Human papillomavirus DNA prevalence and type distribution in anal carcinomas worldwide. Int J Cancer 136(1):98–107
Ali M, Bedair R, El Atti A (2019) Cervical high-risk human papillomavirus infection among women residing in the Gulf Cooperation Council countries: prevalence, type-specific distribution, and correlation with cervical cytology. Cancer Cytopathol 127(9):567–577
Al-Meer FM (2011) Knowledge, attitude and practices regarding cervical cancer and screening among women visiting primary health care in Qatar. East Mediterr Health 17(11):855–861
Arbyn MW (2020) Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health 8(2):191–e203
Atashili JP (2007) Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies. AIDS 22, 1493–1501. AIDS 22:1493–1501
Bosch FM (1995) Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. J Natl Cancer Inst 87(11):796–802
Breitburd F, Kirnbauer R, Hubbert N, Nonnenmacher R (1995) Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection. J Virol 69(6):3959–3963
Brotman RM (2010) Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial and trichomonal genital infection. J Infect Dis 202:1907–1915
Chokunonga E, Ramanakumar A, Nyakabau A (2003) Survival of cervix cancer patients in Harare, Zimbabwe, 1995–1997. Br J Cancer 3(89):65–69
DeSanjosé (2010) Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study. Lancet Oncol 11(11):1048–1056
deSanjosé S (2013) Worldwide human papillomavirus genotype attribution in over 2000 cases of intraepithelial and invasive lesions of the vulva. Eur J Cancer 49(16):3450–3461
Ghazal-Aswad S, Gargash H (2006) Cervical smear abnormalities in the United Arab Emirates: a pilot study in the Arabian Gulf. Acta Cytol 50(1):41–47
Gullen T (1900) Cancer of the Uterus: its pathology, symptomatology, diagnosis and treatment, 1st edn. Appleton, New York
Hausen H, Meinhof W, Scheiber W, Bornkamm G (1974) Attempts to detect virus-specific DNA in human tumors. I. Nucleic acid hybridizations with complementary RNA of human wart virus. Int J Cancer 13(5):650–656
Health TC (2018) HPV and cervical cancer in the MENA region. Retrieved 10 Jan 2020, from https://tuncph.org/en/
IARC (International Agency for Research on Cancer) (2012) A review of human carcinogens. Bookshelf, Lyon
Ibrahim A, Aro A, Rasch V, Pukkala E (2012) Cervical cancer screening in primary health care setting in Sudan: a comparative study of visual inspection with acetic acid and Pap smear. Int J Womens Health 2(4):67–73
Joura E (2014) Attribution of 12 high-risk human papillomavirus genotypes to infection and cervical disease. Cancer Epidemiol Biomarkers Prev 23(10):1997–2008
Khazraji C (2012) International conference on cancer control in Middle-East and Africa. Working group 2: early detection of cervical cancer. Marrakech. Available at: http://www.contrelecancer.ma
Kim JS-G (2013) Model-based impact and cost-effectiveness of cervical cancer prevention in the Extended Middle East and North Africa (EMENA). Vaccine 31:G65–G77
Louie K, de Sanjose S, Mayaud P (2009) Epidemiology and prevention of human papillomavirus and cervical cancer in sub-Saharan Africa: a comprehensive review. Trop Med Int Health 14(1):287–301
Marc A (2020) Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health 19(30482):191–203
Martinez G, Copen C, Abma J (2011) Teenagers in the United States: sexual activity, contraceptive use, and childbearing, 2006–2010 National Survey of Family Growth. Vital Health Stat 23(31):1–35
Moscicki A, Schiffman M, Kjaer S, Villa L (2006) Updating the natural history of HPV and anogenital cancer. Vaccine 24(S3):42–51
Naz U, Hanif S (2014) Agreement between visual inspection with acetic acid and Papanicolaou’s smear as screening methods for cervical cancer. J Coll Physicians Surg Pak 24(4):228–231
Norenhag J, Du J, Olovsson M, Verstraelen H (2020) The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta-analysis. BJOG 127(2):171–180
Ortashi O, Shallal M, Osman N, Raheel H (2012) Knowledge, attitude and practice of school nurses in the United Arab Emirates about HPV infection and vaccine. Asian Pac J Cancer Prev 13(12):6481–6484
Ortashi O, Raheel H, Shalal M, Osman N (2013a) Awareness and knowledge about human papillomavirus infection and vaccination among women in UAE. Asian Pac J Cancer Prev 14(10):6077–6080
Ortashi O, Raheel H, Khamis J (2013b) Acceptability of human papillomavirus vaccination among male university students in the United Arab Emirates. Vaccine 31(44):5141–5144
Papanicolaou G, Traut H (1941) The diagnostic value of vaginal smears in carcinoma of the uterus. Am J Obstet Gynecol 42(2):193–206
Parkin DM, Bray F (2002) Global cancer statistics, 2002. Cancer J Clin 55:74–108
Parkin D, Whelan S, Ferlay J (2002) Cancer incidence in five continents, vol VIII. IARC No.155. Scientific Publication, Lyon
Sait KH (2009) Knowledge, and practices in relation to cervical cancer and its screening among women in Saudi Arabia. Saudi. Saudi Med J 30(9):1208–1212
Schiffman M, Castle P, Jeronimo J, Rodriguez A (2007) Human papillomavirus and cervical cancer. Lancet 370(9590):890–907
Walboomers J, Jacobs MV, Manos M, Bosch FX (1999) Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 98(1):10451482
Wellings K, Collumbien M, Slaymaker E, Singh S (2006) Sexual behaviour in context: a global perspective. Lancet 368(9548):1706–1728
Zare E, Roozbeh N, Akbari PA, Teshnizi SH, Ghazanfarpour M, Abdi F (2020) HPV and its high-risk genotypes in Middle Eastern countries: a meta-analysis. Future Virology 15(9):595–607
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Ortashi, O., Alkalbani, M. (2021). Cervical Cancer Screening in Arab Countries. In: Laher, I. (eds) Handbook of Healthcare in the Arab World. Springer, Cham. https://doi.org/10.1007/978-3-319-74365-3_16-1
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DOI: https://doi.org/10.1007/978-3-319-74365-3_16-1
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