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Contact Allergy to Metalworking Fluids

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Contact Dermatitis

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Abstract

Metalworking fluids (MWF) are frequent causes of occupational irritant and/or allergic contact dermatitis in metalworkers. The most important allergens in water-based MWF are monoethanolamine (MEA) and oxidation products of resin acids. Resin acids are contained in distilled tall oil, which is a widely used basic MWF component. Sensitization to their oxidation products, which are formed in the MWF during the working process, is detected by patch testing with colophonium. Other frequent sensitizers in MWF are formaldehyde, formaldehyde releasers, and other biocides such as isothiazolinones. Various other allergens have been described in individual case reports. Patch testing with the MWF from the patients’ workplace is crucial in the diagnostic work-up of suspected MWF dermatitis.

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  1. Information Network of Departments of Dermatology (IVDK), Institute at the University Medical Center Göttingen, Göttingen, Germany

    Johannes Geier & Holger Lessmann

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  1. Amtssygehuset Gentofte Dept. Dermatology, Hellerup, Denmark

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  2. Federal Institute for Vaccines & Biomed, Paul Ehrlich Institut Federal Institute for Vaccines & Biomed, Langen, Bayern, Germany

    Vera Mahler

  3. Institut le Bel Labo. Dermatochimie, Strasbourg CX, France

    Jean-Pierre Lepoittevin

  4. Hautklinik, Städtische Kliniken Dortmund Klinikzentrum Mitte, Dortmund, Germany

    Peter J. Frosch

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Geier, J., Lessmann, H. (2020). Contact Allergy to Metalworking Fluids. In: Johansen, J., Mahler, V., Lepoittevin, JP., Frosch, P. (eds) Contact Dermatitis. Springer, Cham. https://doi.org/10.1007/978-3-319-72451-5_36-2

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  1. Latest

    Contact Allergy to Metalworking Fluids
    Published:
    10 June 2020

    DOI: https://doi.org/10.1007/978-3-319-72451-5_36-2

  2. Original

    Metalworking Fluids
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    29 September 2019

    DOI: https://doi.org/10.1007/978-3-319-72451-5_36-1

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