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Salivary Gland Disorders and Diseases

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Contemporary Oral Medicine

Abstract

Saliva plays an important role in maintaining healthy oral mucosa and teeth as well as oral function by continually covering and lubricating the oral tissues. Salivary gland dysfunction designates decreased saliva flow rate (salivary gland hypofunction), increased saliva flow rate (sialorrhea or hypersalivation), and changed saliva composition. Xerostomia (the subjective feeling of oral dryness) is often associated with salivary gland hypofunction and may severely affect nutritional intake, social interaction and quality of life. Local or systemic disorders and diseases are common causes of compromised saliva secretion. Some of these are related to gland pathology or to the pathophysiological conditions of the host, whereas others affect the gland innervation or are an iatrogenic result of treatment of a disease (e.g., radiation therapy for head and neck cancer, side effects of medications). In general, many patients suffering from diseases that influence salivary gland function also undergo treatments that may impair saliva secretion and/or induce xerostomia as an adverse effect. Consequently, it can be difficult to distinguish what can be attributed to the disease per se or what can be induced by treatment (e.g., medication intake). Thus, a thorough diagnostic workup and early diagnosis of salivary gland dysfunction are crucial to provide appropriate evidence-based treatment of salivary gland dysfunction to prevent oral sequelae and to initiate individualized alleviating management strategies of xerostomia.

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Author information

Authors and Affiliations

  1. Department of Dentistry and Oral Health, Aarhus University, Aarhus C, Denmark

    Siri Beier Jensen

  2. Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

    Arjan Vissink

  3. UWA Dental School, University of Western Australia, Nedlands, WA, Australia

    Norman Firth

Authors
  1. Siri Beier Jensen
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  2. Arjan Vissink
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  3. Norman Firth
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Corresponding author

Correspondence to Siri Beier Jensen .

Editor information

Editors and Affiliations

  1. UWA Dental School and Oral Health Centre of Western Australia, Faculty of Health and Medical Sciences University of Western Australia, Perth, WA, Australia

    Camile S. Farah

  2. UWA Dental School and Oral Health Centre of Western Australia, Faculty of Health and Medical Sciences University of Western Australia, Perth, WA, Australia

    Ramesh Balasubramaniam

  3. Oral Anatomy, Medicine, and Surgery Section Melbourne Dental School, Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne, Carlton, VIC, Australia

    Michael J. McCullough

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Jensen, S.B., Vissink, A., Firth, N. (2019). Salivary Gland Disorders and Diseases. In: Farah, C., Balasubramaniam, R., McCullough, M. (eds) Contemporary Oral Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-72303-7_19

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  • DOI: https://doi.org/10.1007/978-3-319-72303-7_19

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