Synonyms
Definition
Fly, yeast, mice, rat, frog, worm, sea urchin, etc., this list was not the first part of the Noah’s Arch animals but merely the animal models used by several scientists which have been awarded with the Nobel Prize in Medicine or Physiology. As for example, from the year 2000 to 2017, up to 78% of the awarded Nobel Prizes in Physiology or Medicine concerned pioneering works that have been done, at least partially, on animal models (The Nobel Foundation 2018). Aging research also uses animal models, and the ones presented here have already contributed to draw a global vision of aging, to explore its plasticity and its molecular control.
Overview
The Budding Yeast (Saccharomyces cerevisiae): Toward the Molecular Roots of Aging
As the simplest unicellular model organism described herein (5–10 μm length), the budding yeast, or baker’s yeast, can divide roughly up to 26 times before entering in post-replicative senescence, a process meaning a total arrest of cell...
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Galas, S. (2019). Animal Models of Aging. In: Gu, D., Dupre, M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-69892-2_34-1
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DOI: https://doi.org/10.1007/978-3-319-69892-2_34-1
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