Synonyms
Definition
Aging may be defined in two ways that could be considered equivalent. The first describes the phenomenon as an age-related decline of biological functions, e.g., “progressive loss of function accompanied by decreasing fertility and increasing mortality with advancing age” (Kirkwood and Austad 2000, p. 233); “a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration” (Rose 1991, p. 38); and “any time-dependent change which occurs after maturity of size, form, function is reached and which is distinct from daily, seasonal and other biological rhythms” (Rockstein et al. 1977, p. 4). The second way describes the phenomenon as an age-related increase in mortality, i.e., “increasing mortality with increasing chronological age in populations in the wild” (Libertini 1988, p. 145) or “actuarial senescence” (Holmes and Austad 1995, p. B61), or “age-dependent increase in the risk of death” (Lenart et al. 2018...
References
Austad SN (1989) Life extension by dietary restriction in the bowl and doily spider, Frontinella pyramitela. Exp Gerontol 24:83–92. https://doi.org/10.1016/0531-5565(89)90037-5
Comfort A (1979) The biology of senescence. Livingstone, London
Deevey ES Jr (1947) Life tables for natural populations of animals. Q Rev Biol 22:283–314. https://doi.org/10.1086/395888
Finch CE (1990) Longevity, senescence, and the genome. University of Chicago Press, Chicago
Finch CE, Austad SN (2001) History and prospects: symposium on organisms with slow aging. Exp Gerontol 36:593–597. https://doi.org/10.1016/S0531-5565(00)00228-X
Harper JL (1977) Population biology of plants. Academic, New York
Hill K, Hurtado AM (1996) Ache life history. Aldine De Gruyter, New York
Holmes DJ, Austad SN (1995) Birds as animal models for the comparative biology of aging: a prospectus. J Gerontol A Biol Sci Med Sci 50A:B59–B66
Hyman LH (1951) The invertebrates. Acanthocephala, Aschelminthes, and Entoprocta. The pseudocoelomate bilateria, vol 3. McGrave-Hill, New York
Jazwinski SM (1993) The genetics of aging in the yeast Saccharomyces cerevisiae. Genetica 91:35–51. https://doi.org/10.1007/978-94-017-1671-0_6
Jones OR, Scheuerlein A, Salguero-Gómez R et al (2014) Diversity of ageing across the tree of life. Nature 505:169–173. https://doi.org/10.1038/nature12789
Kirkwood TB, Austad SN (2000) Why do we age? Nature 408:233–238. https://doi.org/10.1038/35041682
Kowald A, Kirkwood TB (2016) Can aging be programmed? A critical literature review. Aging Cell 15(6):986–998. https://doi.org/10.1111/acel.12510
Laws RM (1966) Age criteria for the African elephant, Loxodonta a. africana. E Afr Wildl J 4:1–37. https://doi.org/10.1111/j.1365-2028.1966.tb00878.x
Laws RM (1968) Dentition and ageing of the hippopotamus. E Afr Wildl J 6:19–52. https://doi.org/10.1111/j.1365-2028.1968.tb00899.x
Lenart P, Bienertova-Vasku J, Berec L (2018) Evolution favors aging in populations with assortative mating and strong pathogen pressure. Sci Rep 8:16072. https://doi.org/10.1038/s41598-018-34391-x
Leopold AC (1961) Senescence in plant development. Science 134:1727–1732. https://doi.org/10.1126/science.134.3492.1727
Lesur I, Campbell JL (2004) The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells. MBC Online 15:1297–1312. https://doi.org/10.1091/mbc.e03-10-0742
Libertini G (1988) An adaptive theory of the increasing mortality with increasing chronological age in populations in the wild. J Theor Biol 132:145–162
Libertini G (2013) Evidence for aging theories from the study of a hunter-gatherer people (Ache of Paraguay). Biochem Mosc 78:1023–1032. https://doi.org/10.1134/S0006297913090083
Libertini G (2015a) Phylogeny of aging and related phenoptotic phenomena. Biochem Mosc 80(12):1529–1546. https://doi.org/10.1134/S0006297915120019
Libertini G (2015b) Non-programmed versus programmed aging paradigm. Curr Aging Sci 8(1):56–68
Molisch H (1938) The longevity of plants (trans: Fulling H). Science Press, Lancaster
Noodén LD, Leopold AC (eds) (1988) Senescence and aging in plants. Academic, San Diego
Nussey DH, Froy H, Lemaitre JF et al (2013) Senescence in natural populations of animals: widespread evidence and its implications for bio-gerontology. Ageing Res Rev 12:214–225. https://doi.org/10.1016/j.arr.2012.07.004
Olshansky SJ, Hayflick L, Carnes BA (2002) Position statement on human aging. J Gerontol A Biol Sci Med Sci 57(8):B292–B927. https://doi.org/10.1093/gerona/57.8.B292
Raven PH, Evert RF, Eichhorn SE (1986) Biology of plants, 4th edn. Worth, New York
Ricklefs RE (1998) Evolutionary theories of aging: confirmation of a fundamental prediction, with implications for the genetic basis and evolution of life span. Am Nat 152:24–44. https://doi.org/10.1086/286147
Rockstein M, Chesky JA, Sussman M (1977) Comparative biology and evolution of aging. In: Finch CE, Hayflick L (eds) Handbook of the biology of aging. Van Nostrand Reinhold Company, New York, pp 3–34
Rose MR (1991) Evolutionary biology of aging. Oxford University Press, Oxford
Scott A (1941) Reversal of sex production in Micromalthus. Biol Bull 81:420–431. https://doi.org/10.2307/1537915
Skulachev VP (1997) Aging is a specific biological function rather than the result of a disorder in complex living systems: biochemical evidence in support of Weismann’s hypothesis. Biochem Mosc 62:1191–1195
Skulachev VP (2002) Programmed death phenomena: from organelle to organism. Ann N Y Acad Sci 959:214–237. https://doi.org/10.1111/j.1749-6632.2002.tb02095.x
Sosnowska D, Richardson C, Sonntag WE et al (2014) A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci 69(12):1448–1461. https://doi.org/10.1093/gerona/glt201
Spinage CA (1970) Population dynamics of the Uganda Defassa Waterbuck (Kobus defassa Ugandae Neumann) in the Queen Elizabeth park, Uganda. J Anim Ecol 39:51–78. https://doi.org/10.2307/2889
Spinage CA (1972) African ungulate life tables. Ecology 53:645–652. https://doi.org/10.2307/1934778
Vaupel JW, Baudisch A, Dölling M et al (2004) The case for negative senescence. Theor Popul Biol 65:339–351. https://doi.org/10.1016/j.tpb.2003.12.003
Wikipedia, entry List of world records in masters athletics (consulted on 13/09/2018), data from various sources, https://en.wikipedia.org/wiki/List_of_world_records_in_masters_athletics
Williams GC (1957) Pleiotropy, natural selection and the evolution of senescence. Evolution 11:398–411. https://doi.org/10.1111/j.1558-5646.1957.tb02911.x
Wodinsky J (1977) Hormonal inhibition of feeding of death in octopus. Control by optic gland secretion. Science 198:948–951. https://doi.org/10.1126/science.198.4320.948
Woo HR, Masclaux-Daubresse C, Lim PO (2018) Plant senescence: how plants know when and how to die. J Exp Bot 69(4):715–718. https://doi.org/10.1093/jxb/ery011
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this entry
Cite this entry
Libertini, G. (2019). Aging Definition. In: Gu, D., Dupre, M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-69892-2_29-1
Download citation
DOI: https://doi.org/10.1007/978-3-319-69892-2_29-1
Received:
Accepted:
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-69892-2
Online ISBN: 978-3-319-69892-2
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences