Synonyms
DIP-like change; DIP-like reaction
Definition
Desquamative interstitial pneumonia (DIP)-like pattern is characterized by distal airspace accumulation of pigmented macrophages histologically identical to DIP; however, in contrast to DIP, it is a nonspecific histologic finding seen in association with a preexisting pulmonary process.
Clinical Features
Incidence
The incidence of DIP-like pattern is not known. However, DIP-like pattern is currently accepted as a common occurrence in cigarette smokers presenting with lung diseases other than DIP. DIP-like pattern was first described in 1967 by Scadding and Hinson, shortly after the description of DIP by Liebow et al. (Bedrossian et al. 1977). They reported the finding of DIP in association with usual interstitial pneumonia (UIP) and suggested that DIP was a phase in the development of UIP rather than a distinct interstitial pneumonia. However, DIP-like pattern is now commonly recognized in association with UIP, reported in 12 of...
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Bedrossian, C. W. M., Kuhn, C., III, Luna, M. A., Conklin, R. H., Byrd, R. B., & Kaplan, P. D. (1977). Desquamative interstitial pneumonia-like reaction accompanying pulmonary lesions. Chest, 72, 166–169.
Fraig, M., Shreesha, U., Savici, D., & Katzenstein, A.-L. (2002). Respiratory bronchiolitis: A clinicopathologic study in current smokers, ex-smokers, and never-smokers. The American Journal of Surgical Pathology, 26, 647–653.
Katzenstein, A.-L., Zisman, D. A., Litzky, L. A., Nguyen, B. T., & Kotloff, R. M. (2002). Usual interstitial pneumonia: histologic study of biopsy and explant specimens. The American Journal of Surgical Pathology, 26, 1567–1577.
Vassalo, R., Jensen, E. A., Colby, T. V., Ryu, J. H., Douglas, W. W., Hartman, T. E., & Limper, A. H. (2003). The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis. Chest, 124, 1199–1205.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this entry
Cite this entry
Aubry, MC. (2018). Desquamative Interstitial Pneumonia-Like Pattern. In: Cagle, P.T., Kerr, K.M. (eds) Pulmonary Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-69263-0_323
Download citation
DOI: https://doi.org/10.1007/978-3-319-69263-0_323
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-69262-3
Online ISBN: 978-3-319-69263-0
eBook Packages: MedicineReference Module Medicine